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2025 CPT code 95144

Professional services for supervising the preparation and provision of antigens for allergen immunotherapy; single-dose vial(s).

The number of single-dose vials must be specified on the claim.This code should only be reported when the physician prepares the extract for injection by another entity.Refer to CMS guidelines for further clarification on billing practices.

Modifiers may be applicable depending on the specific circumstances of service. Consult the CPT manual and payer-specific guidelines for appropriate modifier usage.

Allergen immunotherapy is medically necessary for patients with significant allergic reactions to specific substances when other treatments have failed to provide adequate relief. The physician must document the need for immunotherapy based on comprehensive allergy testing and a detailed assessment of the patient's clinical history.

The physician is responsible for determining the appropriate allergens, concentrations, and development of dosing schedules, as well as providing direct supervision of sterile preparation and quality control of the antigens. The physician does not administer the injection.

IMPORTANT:CPT code 95165 is used for preparing multiple-dose vials.If both antigen preparation and administration are performed, component billing should be used.

In simple words: This code covers the doctor's work in overseeing the making and giving of allergy shots.It's used when the doctor prepares individual doses of the medicine that someone else will inject.

This CPT code encompasses the physician's professional services in supervising the preparation and dispensing of antigens for allergen immunotherapy.It specifically applies to single-dose vials, where each vial contains a single dose of antigen for one injection. The code should only be used when a physician prepares the extract for injection by another entity (e.g., a nurse or other qualified healthcare professional). The number of single-dose vials prepared must be specified on the claim.

Example 1: A physician prepares single-dose vials of allergen extract for a patient with seasonal allergies.Another healthcare provider administers the injections., A physician supervises the preparation of single-dose vials of allergen extract in a clinic setting.Nurses administer the injections under the physician's direct supervision., A physician prepares single-dose vials of a specific allergen for a patient with severe allergies, ensuring precise dosage control for each injection.The injections are given by another qualified healthcare provider in a hospital setting.

* Patient's medical history and allergy testing results.* Detailed description of the allergens used and their concentrations.* Dosing schedule.* Number of single-dose vials prepared.* Documentation of physician's direct supervision of antigen preparation (if applicable).* Record of the entity administering the injections.

** Single-dose vials are more costly than multi-dose vials (CPT code 95165) due to the higher preparation costs per dose.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

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