2025 CPT code 96547
(Active) Effective Date: N/A Other Injection and Infusion Services - Chemotherapy administration Medicine Feed
Intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) procedure, including separate incision(s) and closure, when performed; first 60 minutes.
Modifiers may be applicable, such as 52 (Reduced Services), 53 (Discontinued Procedure), or others, based on the circumstances of the procedure.
HIPEC is medically necessary for treating certain cancers that have spread to the peritoneum.The medical necessity should be documented in the patient's medical record and linked to the primary surgical procedure.
The physician or other qualified healthcare professional is responsible for selecting the chemotherapy agent, confirming perfusion equipment settings, supervising the perfusion and manual agitation of the chemotherapy agent, irrigating the abdominal cavity, closing the incisions, and documenting the procedure.
- Medicine
- Chemotherapy Administration and Other Highly Complex Drug or Highly Complex Biologic Agent Administration
In simple words: During an operation, heated chemotherapy is delivered directly into the abdomen for 60 minutes to treat certain cancers.
This add-on code describes the intraoperative perfusion of a heated chemotherapy agent into the abdominal cavity through catheters for the first 60 minutes. It includes chemotherapy agent selection, confirmation of perfusion equipment settings, additional incision(s) for catheter and temperature probe placement, perfusion supervision, manual agitation of the heated chemotherapy agent, irrigation, and closure of wounds related to HIPEC, and documentation. It does not include work related to the primary procedure.
Example 1: A patient undergoing cytoreductive surgery for peritoneal carcinomatosis receives HIPEC with cisplatin for 60 minutes following tumor removal., A patient with appendiceal cancer undergoes surgery and receives HIPEC with mitomycin C for the first hour after resection., A patient with mesothelioma undergoes a pleurectomy/decortication and receives HIPEC for 60 minutes.
Documentation should include the chemotherapy agent used, the perfusion time, details of the HIPEC procedure (including incisions, catheter placement, perfusion parameters, and agitation technique), irrigation details, wound closure information, and any complications.
- Revenue Code: 01D
- RVU: Work RVU: 6.53 (Effective 2025-01-01)
- Global Days: This is an add-on code and does not have its own global period. It is part of the global period for the primary surgical procedure.
- Payment Status: Active
- Modifier TC rule: Modifier TC is not applicable, as this is a surgical service including the technical and professional components.
- Fee Schedule: Information on historical fee schedules can be found via CMS or other fee schedule databases.
- Specialties:Surgical Oncology, Gynecologic Oncology
- Place of Service:Inpatient Hospital, Ambulatory Surgical Center