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BETA v.3.0

2025 ICD-10-CM code A40.0

Sepsis due to Streptococcus, group A.

Use additional code to identify resistance to antimicrobial drugs (Z16.-). Do not use this code for neonatal sepsis (P36.0-P36.1), puerperal sepsis (O85), or streptococcal sepsis during labor (O75.3).

Medical necessity for treatment of sepsis due to Streptococcus, group A, is established by the presence of the infection and systemic symptoms that threaten the patient's life or organ function.

Clinicians should diagnose based on patient history, physical findings, and laboratory tests of blood, urine, wound culture, respiratory secretions, and vomit. Treatment includes antibiotics, and sometimes dialysis, oxygen, intravenous fluids, and surgery (if necessary). Patient education on disease prevention, handwashing, food hygiene, and available vaccines is crucial.

In simple words: Sepsis due to strep A is a serious blood infection caused by strep bacteria. It can be life-threatening and requires urgent medical attention.

Sepsis due to streptococcus, group A, refers to a potentially life-threatening complication of an infection caused when group A streptococcal bacteria enter the bloodstream. This can occur through breaks in the skin, operative incisions, catheterization, or from another infection site like the lungs, urinary tract, intestines, or genital organs.

Example 1: A patient presents with fever, chills, rapid heart rate, and low blood pressure following a skin infection. Blood cultures confirm the presence of Streptococcus, group A, indicating sepsis., Post-operative patient develops sepsis due to Streptococcus, group A, identified through blood cultures. The infection started at the surgical site., A patient with a urinary tract infection caused by Streptococcus, group A, develops systemic symptoms indicative of sepsis, confirmed by laboratory results.

Documentation should include evidence of infection, signs and symptoms of sepsis (e.g., fever, hypotension, tachycardia), and laboratory results confirming the presence of Streptococcus, group A.

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