In simple words: Wound botulism is a rare but serious illness caused by toxins released by the Clostridium botulinum bacteria, which may enter through an open wound, often causing muscle paralysis.

Wound botulism is a rare infectious form of botulism, a rare acquired neuromuscular junction disease with descending flaccid paralysis due to botulinum neurotoxins (BoNTs), produced after infection of wounds by Clostridium botulinum.

Example 1: A patient presents with drooping eyelids, blurred vision, difficulty swallowing, and slurred speech after sustaining a deep puncture wound. Wound botulism is suspected, and the diagnosis is confirmed through laboratory testing., An intravenous drug user develops muscle weakness and paralysis starting in the face and progressing downwards. Upon examination, an infected injection site is discovered, raising suspicion for wound botulism. , Following a traumatic injury, a patient develops signs and symptoms suggestive of botulism, including muscle weakness and difficulty breathing. Wound botulism is considered in the differential diagnosis, especially if the wound was contaminated with soil or debris.

Detailed documentation of the wound, including its location, size, and appearance. Neurological examination findings, including the extent of muscle weakness and paralysis. Laboratory test results confirming the presence of Clostridium botulinum or its toxins. History of injury, drug use, or other potential exposures. Treatment provided, including antitoxin administration and supportive care.

** Wound botulism is most often associated with intravenous drug use, particularly the injection of contaminated heroin. Prompt diagnosis and treatment are essential to prevent potentially fatal respiratory failure.