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2025 ICD-10-CM code A52.05

Other cerebrovascular syphilis.It includes syphilitic cerebral aneurysm (ruptured) (non-ruptured) and syphilitic cerebral thrombosis.

Use additional code to identify resistance to antimicrobial drugs (Z16.-). Refer to ICD-10-CM guidelines for specific coding instructions related to cerebrovascular syphilis.

Medical necessity for the diagnosis and treatment of other cerebrovascular syphilis is established by the presence of characteristic clinical manifestations, confirmed by laboratory and imaging studies. The severity of the condition and potential for serious complications necessitates prompt medical intervention.

Clinicians diagnose cerebrovascular syphilis based on patient history, physical examination, blood tests (including serological tests and PCR), and imaging studies like MRI or MRA. Treatment typically involves penicillin antibiotics, along with patient education about prevention, early detection, and the potential for complications and disability.

In simple words: This code refers to a less common type of brain blood vessel disease caused by syphilis. It includes issues like weakened and bulging blood vessels (aneurysms) and blood clots in the brain, all stemming from untreated syphilis.

Other cerebrovascular syphilis encompasses conditions not specifically classified under other A52.0 subcategories. This includes syphilitic cerebral aneurysms, both ruptured and unruptured, as well as syphilitic cerebral thrombosis.

Example 1: A patient presents with headaches, memory loss, and altered mental status. Diagnostic testing reveals a syphilitic cerebral aneurysm., A patient with a history of untreated syphilis experiences sudden onset of neurological symptoms consistent with a stroke. Imaging confirms a syphilitic cerebral thrombosis., A patient exhibits signs of meningitis and cerebrovascular disease. CSF analysis and serological tests confirm neurosyphilis with cerebrovascular involvement, specifically categorized as "other" due to the presence of both an aneurysm and thrombosis.

Documentation should include evidence of syphilis infection (e.g., serological tests, PCR), neurological symptoms, and imaging findings confirming cerebrovascular involvement (e.g., aneurysm, thrombosis). Details of the patient's history, physical exam, and treatment plan should also be documented.

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