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2025 ICD-10-CM code B25

Cytomegaloviral disease

Code B25 is used for cytomegaloviral disease, excluding congenital CMV (P35.1) and cytomegaloviral mononucleosis (B27.1-). Additional codes may be necessary to document specific manifestations or complications of CMV infection.

Medical necessity for CMV treatment is determined by the severity of the infection, the patient's immune status, and the presence of complications. Treatment is often necessary for newborns with congenital CMV, immunocompromised individuals, and those with severe symptoms.

Diagnosis and treatment of CMV infection are typically managed by physicians, including pediatricians, infectious disease specialists, and transplant specialists, depending on the patient's specific circumstances.

IMPORTANT:Use additional code to identify resistance to antimicrobial drugs (Z16.-). Excludes1: congenital cytomegalovirus infection (P35.1) cytomegaloviral mononucleosis (B27.1-)

In simple words: Cytomegalovirus (CMV) is a common virus that can cause mild flu-like symptoms or no symptoms at all in most healthy people. However, it can cause serious problems for babies born with the infection (congenital CMV) and people with weakened immune systems.

Cytomegaloviral disease is a viral infection caused by the cytomegalovirus (CMV).It is a member of the herpesvirus family. The infection can range from asymptomatic to severe, particularly in newborns and individuals with weakened immune systems.Congenital CMV infection can cause a range of health problems, including hearing loss, developmental disabilities, and other birth defects.

Example 1: A pregnant woman tests positive for CMV but experiences no symptoms.Her infant is born with congenital CMV and develops hearing loss., An immunocompromised patient following an organ transplant develops CMV pneumonia., A healthy toddler attends daycare and develops a mild, self-limiting CMV infection with flu-like symptoms.

Documentation should include evidence of CMV infection through laboratory testing (e.g., viral culture, PCR, serology), the patient's symptoms and clinical presentation, and any related complications or health problems.In cases of congenital CMV, documentation of the mother's CMV status during pregnancy is also important.

** CMV is a common virus, and many people are infected without knowing it.Transmission can occur through contact with bodily fluids, including saliva, urine, blood, breast milk, and semen.

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