2025 ICD-10-CM code B27
(Valid) Effective Date: N/A Infectious and parasitic diseases - Other viral diseases Certain infectious and parasitic diseases Feed
Infectious mononucleosis. Includes: glandular fever, monocytic angina, Pfeiffer's disease.
Medical necessity for evaluation and testing for infectious mononucleosis is based on the presence of characteristic symptoms such as fever, sore throat, lymphadenopathy, and fatigue.Testing helps to confirm the diagnosis and differentiate it from other conditions with similar symptoms, like strep throat, which would require different treatment.
Diagnosis of infectious mononucleosis involves evaluating patient history, physical examination findings, and laboratory tests. These tests may include a complete blood count (CBC), erythrocyte sedimentation rate (ESR), throat cultures, heterophile antibody tests (e.g., Monospot), and polymerase chain reaction (PCR) for EBV DNA.
In simple words: Infectious mononucleosis, often called "mono" or the "kissing disease," is a viral infection usually caused by the Epstein-Barr virus. It spreads through saliva and can cause fever, sore throat, swollen glands, and fatigue. Most people recover in a few weeks, but tiredness can linger.
Infectious mononucleosis, also known as glandular fever, monocytic angina, or Pfeiffer's disease, is a viral illness typically caused by the Epstein-Barr virus (EBV). It is characterized by symptoms such as fever, sore throat, swollen lymph nodes, fatigue, and sometimes an enlarged spleen or liver.While most cases resolve within a few weeks, fatigue can persist for months.
Example 1: A 19-year-old college student presents with fever, sore throat, and swollen lymph nodes in the neck. Blood tests reveal atypical lymphocytes and a positive Monospot test, confirming the diagnosis of infectious mononucleosis., A 10-year-old child experiences mild fatigue and a low-grade fever. Initially thought to be a common cold, the persistence of symptoms and subsequent blood work leads to a diagnosis of infectious mononucleosis., A 45-year-old individual experiences prolonged fatigue, fever, and jaundice.After ruling out other potential causes, a diagnosis of infectious mononucleosis is made, highlighting that the presentation can differ in older adults.
Documentation should include details of the present illness, including the onset and duration of symptoms. Physical exam findings, such as the presence of swollen lymph nodes, tonsillitis, or splenomegaly, should be noted. Results of laboratory tests, including heterophile antibody tests or EBV-specific serologies, should be documented to confirm the diagnosis.
** Although typically caused by EBV, other viruses can also cause mono-like illnesses.It's important to differentiate EBV mononucleosis from these other viral infections, as the management and prognosis might vary.
- Specialties:Infectious Disease, Family Medicine, Internal Medicine, Pediatrics
- Place of Service:Office, Inpatient Hospital, Outpatient Hospital, Urgent Care Facility, Telehealth Provided in Patient’s Home, Telehealth Provided Other than in Patient’s Home