2025 ICD-10-CM code B56.0

Gambiense trypanosomiasis, also known as West African sleeping sickness.

Use additional code to identify resistance to antimicrobial drugs (Z16.-).

Medical necessity for treatment is established by a confirmed diagnosis of Gambiense trypanosomiasis.

Diagnosis based on history of exposure, physical examination, and symptoms. Laboratory tests include blood tests, cerebrospinal fluid (CSF) culture, and microscopic examination of fluids from lymph nodes. Treatment includes combination therapy.

In simple words: West African sleeping sickness, an infection spread by tsetse flies. It causes fever, swollen glands, weakness, aches, and sleep problems. Without treatment, it can be fatal.

Infection due to Trypanosoma brucei gambiense, transmitted by the tsetse fly.Characterized by fever, enlarged lymph nodes, weakness, muscle and joint aches, headache, facial swelling, behavioral changes, and sleep disturbances.If left untreated, can lead to coma and death.

Example 1: A patient presents with fever, swollen lymph nodes, and fatigue after returning from travel in West Africa.Blood tests confirm the presence of Trypanosoma brucei gambiense., A patient experiences progressive neurological symptoms, including sleep disturbances, confusion, and difficulty walking, following a confirmed diagnosis of Gambiense trypanosomiasis., A patient in a coma is diagnosed with Gambiense trypanosomiasis based on CSF analysis and travel history.

Documentation should include travel history, symptoms, physical exam findings, and laboratory results confirming the presence of Trypanosoma brucei gambiense.

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