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2025 ICD-10-CM code C00.6

Malignant neoplasm of the commissure of the lip.

Use additional codes to document any related conditions like tobacco or alcohol use (F10, F17, Z72, Z87.891), or personal history of malignant neoplasm (Z85).

Medical necessity is established by the presence of a malignant neoplasm confirmed by biopsy. Treatment is necessary to prevent local spread and potential metastasis.

Diagnosis and treatment are typically managed by otolaryngologists, head and neck surgeons, or oral and maxillofacial surgeons.Primary care physicians and dentists may play a role in initial detection and referral.

In simple words: This code indicates a cancerous tumor at the corner of the mouth.This area is called the commissure.

This code represents a cancerous growth at the corner of the mouth where the upper and lower lips join.It encompasses various histological types, including squamous cell carcinoma and basal cell carcinoma.

Example 1: A 55-year-old male presents with a non-healing ulcer at the right commissure of his lip. Biopsy confirms squamous cell carcinoma., A 70-year-old female with a history of sun exposure has a persistent, pearly lesion at the left commissure.Diagnosis: Basal cell carcinoma., A 60-year-old male smoker has a growth that extends across both lips at the commissure. This requires documentation as an overlapping lesion C00.8.

Documentation should include location (commissure), laterality (left or right), size and characteristics of lesion,histological confirmation (biopsy results), and any associated symptoms.

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