2025 ICD-10-CM code C21
(Active) Effective Date: N/A Neoplasms - Malignant neoplasms of digestive organs 2: Neoplasms Feed
Malignant neoplasm of anus and anal canal
Medical necessity is based on the presence of malignant neoplasm confirmed by diagnostic testing.
Diagnosis involves physical exam, imaging (CT, MRI, anal ultrasound, PET), biopsy, and lab tests (HIV, Pap smear, tumor markers). Treatment varies based on TNM staging and includes surgery, chemotherapy, and radiation therapy.
In simple words: Cancer of the anus and anal canal. This is where the rectum connects to the anus, the opening where stool leaves the body.
A primary or metastatic malignant neoplasm that affects the anal canal or perianal skin. Representative examples include carcinomas, lymphomas, and melanomas.
Example 1: A patient presents with rectal bleeding and a palpable lump in the anal canal. Biopsy confirms squamous cell carcinoma., An individual with HPV infection experiences persistent anal itching and pain. Further investigation reveals adenocarcinoma of the anal canal., A patient with HIV develops a pigmented lesion near the anus. Biopsy and immunohistochemistry confirm malignant melanoma.
Clinical findings, imaging results, biopsy report, pathology report, and treatment plan.
- Specialties:Oncology, gastroenterology, colorectal surgery, general surgery
- Place of Service:Inpatient Hospital, Outpatient Hospital, Physician's Office