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2025 ICD-10-CM code C53.0

Malignant neoplasm of endocervix.

Use additional codes from Chapter 4 to identify any associated functional activity. Refer to the Table of Neoplasms for accurate topography code selection. For overlapping lesions, use subcategory .8 unless specifically indexed elsewhere.

Medical necessity is established by the presence of a confirmed diagnosis of malignant neoplasm of the endocervix, requiring active treatment.

Diagnosis and treatment of endocervical cancer, which may involve procedures like cervical biopsy, cystoscopy, proctoscopy, imaging tests (X-ray, CT, MRI, PET), chemotherapy, radiation therapy, and surgery such as hysterectomy.

In simple words: This code indicates the presence of cancerous cells in the lining of the cervical canal, which is the passageway connecting the vagina to the uterus.

Malignant neoplasm of the endocervix (the mucous membrane that lines the cervical canal).

Example 1: A 60-year-old female presents with post-coital bleeding and a suspicious lesion on the endocervix. A biopsy confirms a malignant neoplasm., A 45-year-old female with a history of HPV infection is diagnosed with a malignant neoplasm of the endocervix during a routine Pap smear., A 50-year-old female undergoes a radical hysterectomy for a malignant neoplasm of the endocervix that has spread to the surrounding tissues.

Medical history, physical examination findings, results of imaging studies, pathology reports from biopsies, treatment plan, and follow-up notes.

** Excludes1: carcinoma in situ of cervix uteri (D06.-)

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