2025 ICD-10-CM code C72.2

Malignant neoplasm of the olfactory nerve.

Use additional codes from Chapter 4 to identify any functional activity associated with the neoplasm.

Medical necessity is established by the presence of signs and symptoms indicative of a malignant neoplasm of the olfactory nerve, confirmed by diagnostic testing. Treatment is necessary to prevent further growth and spread of the cancer.

Physicians diagnose the disease based on history, symptoms, signs, and ENT (ear, nose, throat) examination. Patients may be asked to identify strong-smelling substances to test olfactory nerve function. Endoscopic and intranasal biopsies help diagnose cancer of the olfactory nerve. Imaging tests such as X-rays, CT scans, and MRI are used to stage the malignancy. Treatment involves chemotherapy, radiation therapy, and surgery.

In simple words: Olfactory neuroblastoma, also known as esthesioneuroblastoma, is a rare cancer that begins in the nose and can spread to the eyes, brain, and other parts of the body. It affects the nerves responsible for the sense of smell.

Malignant neoplasm of the olfactory nerve refers to the abnormal growth of olfactory nerve cells that originates in the nasal cavity and has the potential to spread to the sinuses, eyes, and brain. Risk factors include genetic predisposition, exposure to harmful chemicals, and smoking.

Example 1: A 60-year-old patient presents with loss of smell, persistent nasal congestion, and occasional nosebleeds. After a thorough examination and imaging studies, a diagnosis of malignant neoplasm of the olfactory nerve is confirmed., A 15-year-old patient experiences recurring headaches, facial pain, and a decreased sense of smell. A biopsy and imaging tests reveal a malignant neoplasm of the olfactory nerve., A patient with a history of exposure to wood dust and formaldehyde presents with nasal blockage, watery eyes, and a change in vision. Further investigation confirms a diagnosis of malignant neoplasm of the olfactory nerve.

Documentation should include details of the patient's symptoms, medical history, physical examination findings, results of imaging studies (X-ray, CT scan, MRI), biopsy results, and treatment plan.

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