2025 ICD-10-CM code C7B
(Active) Effective Date: N/A Neoplasms - Secondary neuroendocrine tumors 2: Neoplasms Feed
Secondary neuroendocrine tumors. Use additional code to identify any functional activity.
Medical necessity for treatment of secondary neuroendocrine tumors is based on the extent of metastasis, symptoms, and potential complications. Treatment aims to control tumor growth, alleviate symptoms, and improve quality of life.
Patients with secondary neuroendocrine tumors (NETs) experience symptoms depending upon the site involved; NETs are usually slow-growing and without symptoms early on. The most common manifestation of NETs is carcinoid tumors that can result in carcinoid syndrome due to overproduction of certain hormones and hormone-like substances. General symptoms include high blood pressure, increased heart rate, facial redness, cough, wheezing, diarrhea, shortness of breath, and inflammation of the skin and mucous membranes. Providers diagnose the disease based on history, symptoms, signs, and physical examination. Laboratory tests consist of blood and urine tests to determine hormone levels. The provider may perform a biopsy of a tumor for molecular analysis of genes and other components to identify the type of tumor. For gastrointestinal metastasis, the provider may perform an endoscopy. Imaging tests such as ultrasound, adrenal angiography, X-rays, computerized tomography (CT) scans, magnetic resonance imaging (MRI), bone scintigraphy, and positron emission tomography (PET) are used to diagnose the secondary cancer. Depending on the site and severity of the cancer, treatment involves chemotherapy, radiation therapy, hormone therapy, and surgery such as radiofrequency ablation (RFA) or embolization (cutting off the blood supply) to destroy tumors.
In simple words: Secondary neuroendocrine tumors are cancers that start in one part of the body and spread to other areas. These tumors are made of cells that act like both nerve and hormone-producing cells. They can affect various organs, such as the digestive system, lungs, and pancreas.
Secondary neuroendocrine tumors (NETs) refers to the metastasis (spread) of cancer cells from a primary cancer site to secondary sites. Neuroendocrine tumors (NETs) consist of cells that function like both nerve and endocrine cells, which produce excess hormones and hormone-like substances. NETs may affect the digestive system, lungs, pancreas, liver, kidneys, and reproductive system.
Example 1: A patient with a history of small bowel neuroendocrine tumor presents with liver lesions on CT scan, consistent with metastatic neuroendocrine tumor., A patient with lung neuroendocrine tumor develops bone pain and is found to have multiple bone metastases on bone scan, indicative of secondary neuroendocrine tumor., A patient with pancreatic neuroendocrine tumor presents with abdominal distension and ascites. Imaging reveals peritoneal metastases, confirming secondary neuroendocrine tumor.
Documentation should include the primary site of the neuroendocrine tumor, the location of the secondary tumors, and confirmation of metastasis through imaging or biopsy. Any functional activity associated with the tumor should also be documented.
- Specialties:Oncology, Endocrinology, Gastroenterology, Pulmonology
- Place of Service:Inpatient Hospital, Outpatient Hospital, Physician's Office