2025 ICD-10-CM code C80.0
(Active) Effective Date: N/A Neoplasms - Malignant neoplasm without specification of site 2: Neoplasms Feed
Disseminated malignant neoplasm, unspecified. Cancerous growth affecting multiple body areas, often spreading through the bloodstream, primarily seen in immunocompromised individuals. The specific site(s) affected are unspecified.
Medical necessity for treatment is based on the confirmed diagnosis of disseminated malignancy, the patient's overall health condition, and the potential benefits and risks of the chosen treatment approach.
Diagnosis involves patient history, symptoms, physical examination, and diagnostic procedures (tumor marker tests, biopsy, CT, MRI, PET scans) depending on the site(s) affected. Treatment, including surgery, chemotherapy, and/or radiotherapy, depends on the cancer's stage, location, and resectability.
- 2: Neoplasms
- Malignant neoplasms (C00-C96)Malignant neoplasms, stated or presumed to be primary (of specified sites), and certain specified histologies, except neuroendocrine, and of lymphoid, hematopoietic and related tissue (C00-C75)Malignant neoplasms of ill-defined, other secondary and unspecified sites (C76-C80)
In simple words: Cancer that has spread to many parts of the body. The original location of the cancer is unknown.
Disseminated malignant neoplasm refers to a cancerous growth of cells that has spread to multiple areas of the body.This spread, often occurring via the bloodstream, typically affects individuals with compromised immune systems.The primary site of the neoplasm is unknown.
Example 1: A patient presents with widespread tumors and symptoms in multiple organs, but the origin of the cancer cannot be determined after extensive testing. The diagnosis of disseminated malignant neoplasm, unspecified (C80.0) is given., An immunocompromised patient develops multiple tumors throughout the body. Biopsies and imaging studies confirm malignancy, but a primary site cannot be identified. C80.0 is used., A patient with a history of cancer of unknown origin presents with new tumors in several locations.The new tumors are consistent with metastatic disease. C80.0 is applied.
Documentation should include evidence of widespread malignancy, details of diagnostic tests performed (e.g., biopsy results, imaging reports), and efforts made to identify a primary site, along with the clinical rationale for concluding that the primary site is unknown.
- Specialties:Oncology, Hematology, Internal Medicine, and other specialties depending on the sites involved.
- Place of Service:Inpatient Hospital, Outpatient Hospital, Physician's Office, and other places of service depending on the treatment setting.