2025 ICD-10-CM code C88
Malignant immunoproliferative diseases and certain other B-cell lymphomas.
Medical necessity is established by the presence of signs, symptoms, and diagnostic findings consistent with a malignant immunoproliferative disease or B-cell lymphoma.
Diagnosis involves patient history, physical exam, blood tests (CBC, LDH, kidney and liver function tests), bone marrow biopsy, and imaging (CT, MRI, PET). Treatment may include chemotherapy, radiation, and/or surgery, depending on the stage and severity.
In simple words: This refers to a type of cancer affecting the immune system, specifically the lymphocytes (a type of white blood cell). It causes abnormal cell growth and overproduction of antibodies.
This code represents malignant immunoproliferative diseases where immune cells multiply abnormally, and excessive immunoglobulins are produced. It also includes certain other B-cell lymphomas not classified elsewhere.Excludes1: B-cell lymphoma, unspecified (C85.1-) personal history of other malignant neoplasms of lymphoid, hematopoietic and related tissues (Z85.79).
Example 1: A patient presents with recurring infections, fatigue, and swollen lymph nodes.A biopsy confirms a diagnosis of Waldenström macroglobulinemia, a type of malignant immunoproliferative disease., A patient experiences abdominal pain, weight loss, and night sweats.Imaging reveals enlarged lymph nodes in the abdomen.A biopsy confirms a B-cell lymphoma, not otherwise specified, falling under the C88 category., A child with persistent fever and bone pain undergoes a bone marrow biopsy. The results reveal an aggressive B-cell lymphoma classified under C88.
Documentation should include the type of malignant immunoproliferative disease or B-cell lymphoma, basis for diagnosis (biopsy, imaging, blood tests), stage of the disease, and treatment plan.
- Specialties:Hematology, Oncology
- Place of Service:Inpatient Hospital, Outpatient Hospital, Physician's Office