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2025 ICD-10-CM code C90.10

Plasma cell leukemia not having achieved remission.

Use C90.10 for plasma cell leukemia that has not achieved remission after treatment. Do not use this code for cases in remission (C90.11) or if treatment is successful.

Medical necessity for interventions related to C90.10 must be supported by documentation of active disease, including specific symptoms, laboratory results (elevated plasma cells), and imaging evidence. The chosen treatment approach should be justified based on the patient's overall condition, disease stage, and response to prior therapies, aligning with established clinical guidelines for plasma cell leukemia management.

Clinicians diagnose plasma cell leukemia based on patient history, symptoms, physical examination, blood tests (CBC, LDH, CRP, ESR), bone marrow biopsy, and imaging studies (CT, MRI, PET). Treatment varies depending on the stage and severity, ranging from observation for asymptomatic patients to chemotherapy, stem cell transplantation, radiation therapy, or surgery for advanced cases. Regular follow-up is crucial.

In simple words: This code refers to a type of blood cancer called plasma cell leukemia that hasn't gone into remission, meaning the treatment hasn't been successful in eliminating the disease.

Plasma cell leukemia is a type of multiple myeloma where abnormal plasma cells circulate in the blood. This code signifies that the leukemia has not responded to treatment and remission has not been achieved.

Example 1: A patient with persistent fatigue, bone pain, and recurrent infections undergoes blood tests revealing abnormal plasma cells. A bone marrow biopsy confirms plasma cell leukemia. Despite chemotherapy, the disease persists, and the code C90.10 is used., A patient previously treated for plasma cell leukemia experiences a relapse with increased plasma cells in the blood. This recurrence, despite initial treatment, necessitates further intervention, and C90.10 reflects the current, non-remission state., A patient diagnosed with plasma cell leukemia undergoes stem cell transplantation. However, follow-up examinations reveal persistent abnormal plasma cells in circulation. The code C90.10 denotes the active disease status post-transplant, indicating the need for additional or modified treatment strategies.

Thorough documentation is essential for accurate coding, including complete blood count (CBC) results, bone marrow biopsy reports, imaging findings (CT, MRI, PET), details of treatments received (chemotherapy, radiation, stem cell transplant), physician notes documenting disease progression or lack of remission, and ongoing symptoms.

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