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2025 ICD-10-CM code C95

Leukemia of unspecified cell type. This diagnosis is used when the specific type of leukemia is not documented.

Code C95 should only be used when the specific type of leukemia is not documented. If a more specific diagnosis is available, it should be coded instead.

No modifiers are applicable to ICD-10-CM codes.

The medical necessity for diagnostic testing and treatment of leukemia is based on the patient’s clinical presentation and confirmed diagnosis. Further tests to identify the specific type of leukemia are medically necessary to guide treatment decisions and determine prognosis.

Diagnosis of leukemia involves reviewing the patient’s medical history, conducting a thorough physical examination, and performing laboratory tests such as a complete blood count (CBC), peripheral blood smear, and blood chemistries. Additional tests may include a bone marrow biopsy, fine needle aspiration biopsy, imaging studies (CT, MRI, PET scans), and ultrasound. The appropriate treatment and prognosis depend on the type of leukemia, the stage of the disease, and the patient's age.

In simple words: Leukemia is a type of blood cancer where abnormal blood cells grow out of control. This code is used when the doctor hasn't identified the specific type of leukemia.

A type of cancer that affects the blood and bone marrow, characterized by an uncontrolled increase in abnormal white blood cells. The specific cell type involved in the leukemia is not specified in this code.

Example 1: A 60-year-old patient presents with fatigue, unexplained weight loss, and frequent infections. Initial blood work reveals abnormalities, suggesting leukemia, but further tests are required to determine the specific type., A patient's medical record mentions "leukemia" without specifying the type or cell lineage. In the absence of more specific information, C95 is used., A child exhibits symptoms like bruising easily, bone pain, and swollen lymph nodes. While leukemia is suspected, further diagnostic workup is pending to identify the exact cell type and classify the leukemia accurately.

Documentation should include the patient’s presenting symptoms, physical exam findings, relevant laboratory results (CBC, peripheral smear, blood chemistries), bone marrow biopsy results (if performed), and imaging studies (if performed).If a more specific diagnosis is available, it should be coded instead of C95.

** Excludes1: personal history of leukemia (Z85.6)

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