2025 ICD-10-CM code D21.4
(Active) Effective Date: N/A Benign neoplasms - Benign neoplasm of connective and other soft tissue of abdomen Chapter 2: Neoplasms (C00-D49) Feed
Benign neoplasm of connective and soft tissue of the abdomen.This includes benign neoplasms of blood vessels, bursae, cartilage, fascia, fat, ligaments (except uterine), lymphatic channels, muscle, synovia, and tendons (sheaths).
Medical necessity is based on the presence of symptoms, the size and location of the neoplasm, and the potential for complications (e.g., obstruction, pain, interference with organ function). Asymptomatic, small, and stable neoplasms may not require intervention.
The provider diagnoses the condition based on the patient’s history, physical examination, and imaging studies (X-ray, CT, MRI, PET). Laboratory tests, such as cytogenetic analysis of a tissue sample, may be performed. Biopsy (fine needle aspiration or open biopsy) of the mass may be necessary for definitive diagnosis. Treatment, if required, involves surgical excision of the mass and supportive care to relieve symptoms.
In simple words: A non-cancerous lump in the connective tissue (like muscle, fat, or ligaments) or other soft tissues of your belly area.
Benign neoplasm of connective and soft tissue of the abdomen refers to an abnormal mass of cells that lacks the ability to penetrate the neighboring tissues. Connective tissues (muscles, fascia and synovia, tendons, ligaments, and cartilage) connect, protect, support, and surround bones, organs, and other structures, and other soft tissues include stromal tissues, blood, and lymph vessels. This code represents a benign neoplasm of connective and other soft tissues of the abdomen not specifically represented by another code.
Example 1: A patient presents with abdominal discomfort and a palpable mass. Imaging reveals a benign lipoma in the abdominal wall., During a routine abdominal ultrasound, a benign fibroma is discovered in the mesentery of a patient., A patient undergoes surgery for an inguinal hernia, and a benign leiomyoma of the abdominal wall musculature is incidentally discovered and excised.
Documentation should include the location and size of the neoplasm, the type of connective or soft tissue involved, and any associated symptoms.Confirmation of the diagnosis by biopsy (pathology report) is essential. Imaging reports and cytogenetic analysis results should also be included, if performed.
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