2025 ICD-10-CM code D47.Z9
Neoplasms of uncertain behavior of lymphoid, hematopoietic, and related tissue are tumors that cannot be definitively classified as benign or malignant based on initial histologic examination. This code is used for specific types not otherwise classified.
Medical necessity is established by the diagnostic workup to evaluate signs and symptoms suggestive of a neoplasm and the need for further investigation and potential treatment based on the uncertain behavior of the neoplasm.
Diagnosis and treatment are based on patient history, physical examination, laboratory tests (CBC, peripheral blood smear, chemistry profile), biopsy or FNA, microscopic histology and cytology, genetic analysis, and imaging studies (ultrasound, CT, MRI, PET). Treatment may involve close follow-up, supportive care, surgical excision, radiation therapy, and/or chemotherapy.
- Neoplasms (C00-D49)
- Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes (D37-D48)
In simple words: This code refers to a tumor in your lymph or blood-forming tissues. Doctors aren't sure if it's cancerous or not based on the initial tests. More testing may be needed.
Other specified neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue refer to a pathological diagnosis that describes tumors which cannot be confirmed as benign or malignant based on histologic examination of cells from a biopsy specimen, i.e., the cell type cannot be definitively determined. The provider documents a specific type of neoplasm of uncertain behavior of lymphoid, hematopoietic or related tissue not represented by another code.
Example 1: A patient presents with enlarged lymph nodes and fatigue. Biopsy results are inconclusive, showing features of both benign and malignant histiocytic cells. D47.Z9 is used while awaiting further immunohistochemical analysis., Following a transplant, a patient develops a lymphoproliferative disorder. Biopsy confirms it is not lymphoma or other specific entity. D47.Z1 (PTLD) is a more specific code within D47.Z and should be used instead of D47.Z9 in this case., A patient with abnormal bleeding and clotting undergoes bone marrow biopsy. The pathologist diagnoses a myeloproliferative neoplasm, but cannot classify it further. Additional tests are ordered to determine if it is a specific type of myeloproliferative neoplasm.D47.Z9 is appropriate while awaiting results.
Complete clinical documentation of the patient's signs, symptoms, diagnostic workup including biopsy results, and the pathologist's diagnosis of a specific neoplasm of uncertain behavior not captured by other codes. Ideally, the final pathology report should be reviewed before assigning a code.
** It is crucial to have complete pathology reports for accurate coding. This code should be used as a placeholder while awaiting further diagnostic clarification. Regular follow-up and further investigations are usually necessary for definitive diagnosis and treatment planning.
- Payment Status: Active
- Specialties:Hematology, Oncology, Pathology, Internal Medicine
- Place of Service:Inpatient Hospital, Outpatient Hospital, Physician's Office, Independent Clinic, Laboratory