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2025 ICD-10-CM code D57

Sickle cell disorders.Use additional code for any associated fever.

Refer to the official ICD-10-CM coding guidelines for detailed instructions on proper code assignment and sequencing.

Modifiers may apply depending on the circumstances of the encounter. Consult the appropriate coding guidelines for specific details.

Medical necessity for treatment of sickle cell disease is established by the presence of symptoms and complications consistent with the diagnosis, confirmed by laboratory testing. Treatment is medically necessary to alleviate pain, prevent organ damage, and improve quality of life.

Diagnosis and management of sickle cell disease, including history taking, physical examination, laboratory testing (CBC, blood smear), and treatment (blood transfusions, pain management, hydroxyurea, etc.).Referral to hematology or specialized care as needed.

IMPORTANT:Use additional code R50.81 for associated fever.Excludes other hemoglobinopathies (D58.-).

In simple words: Sickle cell disease is an inherited condition where your red blood cells are shaped like sickles (crescent moons) instead of round discs. These misshapen cells don't carry oxygen as well and can block blood flow, leading to pain, infections, and other health problems.Treatment depends on the severity and may involve blood transfusions or other medications.

Sickle cell disorder (SCD) is a group of inherited blood disorders characterized by the production of abnormal hemoglobin, leading to misshapen, rigid, sickle-shaped red blood cells. These cells impede blood flow, causing various complications such as pain crises, anemia, organ damage, and infections.The severity varies widely, and symptoms can range from mild to life-threatening. Diagnosis involves blood tests to identify abnormal hemoglobin and characteristic sickle-shaped red blood cells. Treatment may include blood transfusions, hydroxyurea, and in severe cases, bone marrow transplantation.

Example 1: A 25-year-old African-American female presents to the emergency department with severe pain in her abdomen and legs. She has a history of sickle cell anemia and is currently experiencing a vaso-occlusive crisis.The physician orders blood work, pain medication, and intravenous fluids., A 10-year-old boy with sickle cell disease is admitted to the hospital for acute chest syndrome. He is experiencing shortness of breath and chest pain.Treatment includes oxygen therapy, antibiotics, and close monitoring of his respiratory status., A 50-year-old male with a history of sickle cell disease is seen in the hematology clinic for routine follow-up. The physician reviews his blood work, assesses his overall health, and discusses preventive measures such as hydration and avoiding triggers for crises.

Complete blood count (CBC), peripheral blood smear, hemoglobin electrophoresis, family history of sickle cell disease, detailed description of presenting symptoms (pain location, severity, duration), response to treatment, and any complications.

** Further characterization of the specific type of sickle cell disease may be necessary in some cases, utilizing additional codes as needed.

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