2025 ICD-10-CM code D61.82
Myelophthisis is a disease of the bone marrow characterized by fibrosis, reducing its ability to produce blood cells. This often leads to pancytopenia.
Medical necessity for treatments related to myelophthisis is established by the severity of the condition and the underlying cause. Treatment is directed at improving blood cell counts, managing symptoms, and treating the underlying disease process.
Clinicians diagnose myelophthisis based on patient history, physical examination, and laboratory tests like CBC and bone marrow biopsy. Treatment focuses on the underlying cause, often requiring specialized care from hematologists or oncologists.
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
- Aplastic and other anemias and other bone marrow failure syndromes (D60-D64)
In simple words: Myelophthisis is a condition where the bone marrow, which makes blood cells, gets replaced by scar tissue or abnormal cells. This can lead to fewer red blood cells, white blood cells, and platelets, causing tiredness, infections, and easy bruising. It can be caused by cancer, infections, or other diseases.
Myelophthisis is a serious bone marrow disorder characterized by the replacement of hematopoietic tissue with fibrous tissue or other abnormal cells. This replacement disrupts the normal production of blood cells, leading to a variety of symptoms and complications.Common causes include malignancies like leukemia or metastatic cancers, infections (tuberculosis, fungal infections), and granulomatous diseases like sarcoidosis.Symptoms may include fatigue, weakness, pallor, bruising, petechiae, fever, and frequent infections. Diagnosis typically involves a complete blood count (CBC), bone marrow biopsy, bone scan, and tests specific to suspected infectious agents. Treatment focuses on addressing the underlying cause and providing supportive care such as blood transfusions and medications to manage infections.
Example 1: A patient with a history of breast cancer presents with fatigue, pallor, and recurrent infections. A bone marrow biopsy reveals fibrosis consistent with myelophthisis due to metastatic cancer., A patient with long-standing tuberculosis develops pancytopenia. Further investigation reveals myelophthisis as a complication of the chronic infection., A patient undergoes a bone marrow biopsy for unexplained anemia, which reveals granulomas and fibrosis.After additional testing, sarcoidosis is diagnosed as the underlying cause of the myelophthisis.
Documentation should include complete blood count (CBC) results, bone marrow biopsy findings, imaging studies (if performed), and any other relevant test results.The underlying cause of myelophthisis should be clearly documented, along with associated signs and symptoms.
- Specialties:Hematology, Oncology, Internal Medicine, Infectious Disease
- Place of Service:Inpatient Hospital, Outpatient Hospital, Office