2025 ICD-10-CM code D84.82
Immunodeficiency due to drugs and external causes.
Medical necessity is established by the presence of a weakened immune system directly resulting from drug use or an external cause. This should be supported by clinical findings such as recurrent infections, laboratory tests showing reduced immune cell counts or function, or other evidence of impaired immune response.
Clinicians should document the specific drug or external cause contributing to the immunodeficiency, along with any associated infections or complications.
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
- D84 Other immunodeficienciesD84.8 Other specified immunodeficienciesD84.82 Immunodeficiency due to drugs and external causes
In simple words: This code signifies a weakened immune system caused by medications or external factors.
Immunodeficiency due to drugs and external causes.
Example 1: A patient undergoing chemotherapy develops a weakened immune system, documented as immunodeficiency due to drugs (D84.821)., A patient with a history of splenectomy due to trauma presents with recurrent infections, coded as immunodeficiency due to external causes (D84.822)., A patient on long-term immunosuppressant medication for an autoimmune disorder experiences frequent infections, coded as immunodeficiency due to drugs (D84.821).
Documentation should specify the causal relationship between the drug or external cause and the immunodeficiency.Additional codes should be used for any associated conditions, such as infections or adverse drug reactions. If the cause is drug-related, the specific drug should be documented. If due to external causes, the nature of the external cause should be clearly noted, such as radiation exposure or splenectomy.
** This code represents a billable ICD-10-CM diagnosis code.It can be used for claims and reimbursement purposes when submitted correctly. Please refer to current coding and payer guidelines for further details.
- Specialties:Immunology, Hematology, Oncology, Infectious Disease
- Place of Service:Inpatient Hospital, On Campus-Outpatient Hospital, Off Campus-Outpatient Hospital, Office, Independent Clinic, Federally Qualified Health Center