2025 ICD-10-CM code E27.49
Other adrenocortical insufficiency. This code is used when the provider documents a type of adrenocortical insufficiency not otherwise classified.
Medical necessity is established by the clinical presentation of adrenal insufficiency and supporting laboratory/imaging evidence confirming the diagnosis and excluding other forms of adrenal dysfunction.
Diagnosis involves reviewing patient history, physical examination, and lab tests (blood and urine) to measure cortisol, ACTH, and aldosterone levels. Imaging studies (MRI, CT) may be used to visualize the adrenal glands and detect abnormalities.
- Chapter 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89)
- E27 - Other disorders of adrenal glandE27.4 - Other and unspecified adrenocortical insufficiencyE27.49 - Other adrenocortical insufficiency
In simple words: The adrenal glands, located above the kidneys, produce hormones essential for various bodily functions.Other adrenocortical insufficiency means these glands aren't producing enough of these hormones, specifically cortisol (which manages stress and metabolism) and sometimes aldosterone (which regulates salt and water balance). This can lead to symptoms like fatigue, weight loss, and low blood pressure.
Other adrenocortical insufficiency refers to the underproduction of adrenal hormones, primarily cortisol, and sometimes aldosterone.This condition is distinct from primary adrenocortical insufficiency (Addison's disease) and drug-induced forms.It encompasses conditions like adrenal hemorrhage or infarction leading to insufficient hormone production.
Example 1: A patient presents with fatigue, weight loss, and low blood pressure.Lab results reveal low cortisol and aldosterone levels, and imaging shows evidence of adrenal hemorrhage. E27.49 is used to code the other adrenocortical insufficiency due to the hemorrhage., Following an abdominal injury, a patient develops symptoms consistent with adrenal insufficiency. Imaging reveals adrenal infarction.E27.49 is used to document the other adrenocortical insufficiency resulting from the infarction., A patient with a history of autoimmune disease develops adrenal insufficiency.Testing confirms low cortisol levels, but the presentation does not align with typical Addison's disease or drug-induced causes. E27.49 is used to code the other adrenocortical insufficiency.
Documentation should include signs and symptoms, laboratory results (cortisol, ACTH, aldosterone), imaging findings (if applicable), and any relevant history (e.g., trauma, autoimmune disease).
** Conditions like Waterhouse-Friderichsen syndrome and adrenoleukodystrophy are excluded from this code and have their own specific ICD-10-CM codes.
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- Specialties:Endocrinology, Internal Medicine
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