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2025 ICD-10-CM code E28

Ovarian dysfunction

Note that neoplasms affecting the ovaries are coded in Chapter 2.However, E28 can be used as an additional code to indicate functional activity or dysfunction associated with a neoplasm.

Medical necessity for services related to ovarian dysfunction must be established based on the individual patient's clinical presentation and the specific treatment being provided.The documentation should clearly link the symptoms and diagnostic findings to the medical necessity of the intervention.

The ovaries are two small female reproductive glands that produce eggs and secrete hormones like estrogen, testosterone, and progesterone.Signs and symptoms of ovarian dysfunction vary, but can include changes in menstruation (heavy, light, or absent periods), infertility, pelvic pain, bloating, nausea and vomiting, painful intercourse, frequent urination, decreased libido, mood swings, excessive hair growth, anxiety, weight gain, and depression.

In simple words: Ovarian dysfunction means the ovaries aren't working properly. This could involve issues like producing too much or too little of certain hormones, polycystic ovary syndrome (PCOS), early menopause, or when the ovaries stop working as they should before natural menopause.

Ovarian dysfunction refers to a dysfunction of the ovaries, including but not limited to overproduction of estrogen or androgen, polycystic ovarian syndrome, primary ovarian failure, and premature menopause.

Example 1: A 25-year-old female presents with irregular periods, acne, and excessive hair growth. After diagnostic testing, she is diagnosed with polycystic ovary syndrome (PCOS), which is coded as E28., A 38-year-old female experiences hot flashes, night sweats, and irregular periods.Blood tests reveal elevated FSH levels, indicating premature ovarian failure, coded as E28., A 16-year-old female has never had a menstrual period.She is diagnosed with primary ovarian insufficiency after testing, which is also coded as E28.

Documentation should include the patient's history, physical examination findings, and results of diagnostic studies such as hormone levels (e.g., estrogen, progesterone, FSH, LH, testosterone) and imaging studies (e.g., ultrasound) that confirm the diagnosis of ovarian dysfunction.

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