2025 ICD-10-CM code E83.111
(Active) Effective Date: N/A Endocrine, Nutritional and Metabolic Diseases - Disorders of iron metabolism 4 Feed
Hemochromatosis due to repeated red blood cell transfusions.Iron overload caused by multiple blood transfusions.
Medical necessity for treatment of hemochromatosis is established by the presence of iron overload secondary to repeated transfusions, as evidenced by elevated iron studies and/or clinical manifestations of iron toxicity.Treatment aims to prevent or minimize organ damage from iron deposition.
The provider is responsible for diagnosing and managing hemochromatosis due to repeated red blood cell transfusions.This includes evaluating the patient's history, signs, symptoms, conducting a physical examination, and ordering appropriate diagnostic tests such as CBC, serum iron tests, liver function tests (AST and ALT), and potentially an MRI. Treatment includes iron chelation therapy to remove excess iron, and in severe cases, organ transplantation may be necessary.
In simple words: A condition where repeated blood transfusions cause a buildup of iron in the body, potentially harming organs.This is because red blood cells contain iron, and the body has difficulty removing large amounts of excess iron.
Hemochromatosis resulting from repeated red blood cell transfusions. This condition involves excessive iron accumulation in the body due to the iron contained in transfused red blood cells, leading to iron overload and potential organ damage.
Example 1: A patient with severe beta-thalassemia major requiring chronic red blood cell transfusions develops symptoms of hemochromatosis, including liver enlargement and elevated liver enzymes., A patient with sickle cell disease who has received numerous blood transfusions over many years presents with fatigue, joint pain, and skin discoloration. Diagnostic testing confirms iron overload and hemochromatosis., A patient with aplastic anemia who undergoes regular transfusions develops cardiac abnormalities due to iron deposition in the heart muscle, a complication of transfusional hemochromatosis.
Documentation should include the patient's underlying condition necessitating transfusions, transfusion history (number of units, frequency), clinical findings suggestive of hemochromatosis (e.g., fatigue, abdominal pain, joint pain, skin changes), laboratory results (serum iron, ferritin, liver function tests), and imaging findings (if applicable, such as MRI for organ assessment).
- Payment Status: Active
- Specialties:Hematology, Hepatology, Cardiology
- Place of Service:Inpatient Hospital, Outpatient Hospital, Physician's Office