In simple words: Meconium ileus is a blockage in a newborn's intestines.It happens when their first poop is too thick and sticky to pass, often due to a condition called cystic fibrosis. Cystic fibrosis makes the mucus in the body very thick.

Meconium ileus in cystic fibrosis refers to a blockage in the small intestine of a newborn.It occurs when the first stool (meconium) is unusually thick and sticky due to cystic fibrosis, causing an obstruction.Cystic fibrosis is a genetic disorder characterized by the buildup of thick mucus in various organs.

Example 1: A newborn diagnosed with cystic fibrosis presents with abdominal distension and vomiting, unable to pass meconium within the first 24 hours. This is consistent with meconium ileus and requires further investigation., A prenatal ultrasound reveals echogenic bowel, raising suspicion for cystic fibrosis. After birth, the baby fails to pass meconium, confirming the diagnosis of meconium ileus in cystic fibrosis., A newborn with cystic fibrosis develops meconium ileus requiring surgical intervention to remove the blockage and alleviate the intestinal obstruction.

Documentation should include the presence of cystic fibrosis, the inability to pass meconium in the first 24 hours of life, associated symptoms like abdominal distention and vomiting, results of diagnostic tests (newborn screening, genetic tests, ultrasound), and treatment provided (surgical or non-surgical).

** Cystic fibrosis is an autosomal recessive genetic disorder. Meconium ileus is a common initial presentation of cystic fibrosis.