2025 ICD-10-CM code E85.9
(Active) Effective Date: N/A Metabolic disorders - Amyloidosis 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89) Feed
Amyloidosis, unspecified.
The medical necessity for the workup and treatment of amyloidosis must be documented. This should include the severity of the patient's symptoms, the impact on their daily life, and the potential complications of the disease.The rationale for any specific treatments, such as chemotherapy, stem cell transplantation, or organ transplantation, should also be documented.
Clinicians must document the patient's signs, symptoms, and diagnostic results to support the diagnosis of amyloidosis. This includes details of any organ involvement and any underlying conditions.If the specific type of amyloidosis is identified, the more specific code should be used.
- 4: Endocrine, Nutritional and Metabolic Diseases (E00-E89)
- E85: AmyloidosisE85.9: Amyloidosis, unspecified
In simple words: This code indicates a condition where abnormal protein fibers, called amyloids, are deposited in the body's organs and tissues. The exact type of amyloidosis is unknown in this case.
A condition characterized by the buildup of amyloid proteins in various organs or tissues.This code is used when the specific type of amyloidosis is not documented.
Example 1: A patient presents with fatigue, weight loss, and shortness of breath. After diagnostic testing, including a tissue biopsy, amyloidosis is diagnosed, but the specific type is not yet determined. E85.9 is used until further testing identifies the specific type., A patient with a history of multiple myeloma develops kidney problems.A biopsy reveals amyloid deposits in the kidneys. E85.9 is used initially, but after further workup, the diagnosis is refined to AL amyloidosis (E85.81)., A patient undergoing dialysis develops carpal tunnel syndrome and other peripheral neuropathy symptoms.Amyloid deposits are found, but further testing is required to classify the type of amyloidosis. E85.9 is used as a placeholder until the specific type is identified, potentially related to dialysis (E85.3).
Documentation should include signs and symptoms, physical exam findings, laboratory results (e.g., blood and urine tests, biopsy results), and imaging studies (e.g., echocardiogram, CT, MRI). The documentation should also include details of any organ involvement, such as the heart, kidneys, liver, or nervous system, and any underlying conditions that may be contributing to the amyloidosis.
** Excludes2: Alzheimer's disease (G30.0-)
- Specialties:Internal medicine, nephrology, cardiology, hematology, neurology
- Place of Service:Inpatient Hospital, Outpatient Hospital, Office, Independent Clinic