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BETA v.3.0

2025 ICD-10-CM code E89.1

Postprocedural hypoinsulinemia is a condition characterized by low insulin levels in the blood following a medical procedure.

Code E89.1 should be used as a secondary code to the underlying condition causing the hypoinsulinemia.It is not to be used for transient postprocedural hypoglycemia (E16.2).

Medical necessity is established by the presence of hypoinsulinemia following a medical procedure, causing clinically significant symptoms or requiring intervention to prevent complications.

Clinicians diagnose postprocedural hypoinsulinemia based on history, physical examination, and symptoms. Laboratory testing includes blood glucose, lipid profile, HbA1c, urinary albumin, and anti-insulin antibody levels. Treatment involves insulin therapy, diet management, and blood glucose monitoring.

IMPORTANT: If applicable, use additional codes for diabetes mellitus (E13.-), acquired absence of pancreas (Z90.41-), and insulin use (Z79.4).

In simple words: Postprocedural hypoinsulinemia means low blood insulin levels after a medical procedure. Insulin helps your body use sugar for energy. This condition can cause symptoms like excessive thirst and urination, intense hunger, tiredness, weight loss, slow wound healing, blurry vision, and frequent infections. Doctors diagnose it through medical history, physical exam, and blood tests. Treatment often involves insulin shots, a special diet, and checking blood sugar levels.

Postprocedural hypoinsulinemia refers to insufficient insulin levels in the blood after a surgical or other medical procedure.Insulin, a hormone produced by the pancreas, helps the body use glucose (sugar) for energy.Symptoms can mimic uncontrolled diabetes, such as increased urination and thirst, extreme hunger, fatigue, weight loss, slow-healing sores, blurred vision, and frequent infections. Diagnosis involves patient history, physical examination, and laboratory tests (fasting plasma glucose, 2-hour plasma glucose, lipid profile, HbA1c, urinary albumin, and anti-insulin antibodies). Treatment includes insulin injections, dietary management, and blood glucose monitoring.

Example 1: A patient develops low blood sugar after a partial pancreatectomy. The diagnosis is confirmed with blood tests, and insulin therapy is initiated., Following a liver transplant, a patient experiences symptoms of hypoinsulinemia, including increased thirst and urination. Lab results show low insulin levels, prompting dietary adjustments and glucose monitoring., After gastric bypass surgery, a patient presents with fatigue, weight loss, and frequent infections.Postprocedural hypoinsulinemia is suspected, and further investigations are ordered to confirm the diagnosis and guide treatment.

Documentation should include the procedure performed, onset of symptoms, laboratory results (glucose, HbA1c, etc.), and treatment plan (insulin dosage, dietary modifications).

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