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2025 ICD-10-CM code E89.5

Postprocedural testicular hypofunction:A condition where the testicles produce insufficient hormones, primarily testosterone, due to prior surgery, chemotherapy, or radiation therapy.

All neoplasms, whether functionally active or not, are classified in Chapter 2. This code can be used in conjunction with codes from Chapter 2 to indicate functional activity or hyper/hypofunction associated with neoplasms.

Medical necessity must be established by documenting the relationship between the prior procedure and the subsequent testicular hypofunction. The documentation should support the need for diagnostic testing and any subsequent treatment, like hormone replacement therapy.

Clinicians diagnose this condition based on patient history, symptoms, physical examination, and blood tests for testosterone levels. Treatment may involve hormone replacement therapy depending on the severity of the hypofunction.

In simple words: This condition occurs when a man's testicles don't produce enough hormones, especially testosterone, after surgery, chemotherapy, or radiation therapy.This can cause several issues like low sex drive, tiredness, and problems with fertility.

Postprocedural testicular hypofunction refers to reduced testicular hormone production (primarily testosterone) following a medical procedure such as surgery, chemotherapy, or radiation therapy. This can lead to various symptoms including decreased libido, depression, fatigue, infertility, weight gain, and osteoporosis.

Example 1: A patient experiences decreased libido and fatigue following testicular surgery. After blood tests reveal low testosterone levels, he is diagnosed with E89.5 and begins hormone replacement therapy., A man undergoing chemotherapy for cancer develops symptoms consistent with low testosterone. After his testicles are determined to be the source of the hormonal deficiency and linked to chemotherapy, E89.5 is used for coding., After radiation therapy for prostate cancer, a patient presents with infertility and weight gain. Low testosterone levels confirm postprocedural testicular hypofunction, and he receives a diagnosis of E89.5.

Documentation should include the type of procedure (surgery, chemotherapy, radiation) that preceded the hypofunction, signs and symptoms, physical examination findings, testosterone levels, and the treatment plan.

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