In simple words: This code signifies severe memory loss and other cognitive problems due to a physical condition, along with mood issues like depression or lack of interest.

Major neurocognitive disorder in other diseases classified elsewhere, severe, with mood disturbance such as depression, apathy, or anhedonia.This code should be used when a patient has severe dementia caused by a documented physiological condition other than those specifically listed elsewhere in the ICD-10-CM, and this dementia includes notable mood disturbances.

Example 1: A patient with Huntington's disease (G10) exhibits severe memory impairment, difficulty with executive functions, and significant depressive symptoms., A patient with severe dementia resulting from traumatic brain injury (S06.-) experiences mood swings characterized by marked apathy and emotional lability. , A patient with a history of systemic lupus erythematosus (M32.-) develops severe cognitive decline and persistent anhedonia, impacting their daily activities.

Documentation should clearly link the dementia and the mood disturbance to the underlying physiological condition. The severity of the dementia should be substantiated by objective cognitive assessments and impact on daily functioning.The specific type of mood disturbance, such as depression, apathy, or anhedonia, should also be clearly documented.