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2025 HCPCS code J0585

Injection, onabotulinumtoxinA, 1 unit

This code is for the drug only and does not include administration. Check payer guidelines for appropriate administration codes.

Modifiers may be applicable. Refer to specific payer guidelines.

Medical necessity must be established for non-cosmetic uses. This may include failed conservative therapies, functional limitations, and impact on quality of life.

The clinician is responsible for the proper assessment, diagnosis, determination of medical necessity, selection of injection site(s), administration of the injection, and patient education.

IMPORTANT:Related HCPCS codes for other botulinum toxins include:* J0586: Injection, abobotulinumtoxinA, 5 units* J0587: Injection, rimabotulinumtoxinB, 100 units* J0588: Injection, incobotulinumtoxinA, 1 unit

In simple words: This code is for one unit of Botox (onabotulinumtoxinA) injection. Botox is used to treat muscle spasms, excessive sweating, migraines, and some bladder problems. It's also used for cosmetic purposes to reduce wrinkles.

OnabotulinumtoxinA is a neurotoxin used to treat various medical conditions by blocking nerve activity in muscles.This code represents one unit of onabotulinumtoxinA administered via intramuscular, intradetrusor, or intradermal injection. It is used to treat conditions such as blepharospasm, strabismus, cervical dystonia, limb spasticity, chronic migraine, urinary incontinence, and axillary hyperhidrosis.It is also used cosmetically to reduce wrinkles.

Example 1: A patient with chronic migraine receives multiple injections of J0585 across their forehead and temples for migraine prevention., A patient with overactive bladder receives J0585 injections into the detrusor muscle to improve bladder control., A patient receives J0585 injections for cosmetic reduction of glabellar lines (frown lines between the eyebrows).

Documentation should include diagnosis, medical necessity, injection sites, number of units injected, and any adverse reactions.

** Prior authorization might be required for certain indications. This drug should not be used in patients with a known hypersensitivity to botulinum toxin.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

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