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2025 ICD-10-CM code K75.3

Granulomatous hepatitis, not elsewhere classified.

Refer to the official ICD-10-CM coding guidelines for complete instructions on code selection and sequencing.Ensure proper exclusion criteria are met before assigning K75.3.

Medical necessity for coding K75.3 is established by the presence of clinical symptoms (e.g., fatigue, jaundice, abdominal pain), abnormal liver function tests, and histopathological confirmation of granulomatous hepatitis on liver biopsy.The absence of other identifiable causes for the liver inflammation must be documented.

Gastroenterologist, Hepatologist

IMPORTANT:Excludes: Acute or subacute hepatitis (K72.0-), Chronic hepatitis NEC (K73.-), Viral hepatitis (B15-B19), Toxic liver disease (K71.-)

In simple words: This code describes a type of liver inflammation caused by granuloma formation (small clumps of immune cells).It's used when the cause of the liver inflammation isn't specified or doesn't match other specific liver conditions.

Granulomatous hepatitis, not elsewhere classified.This ICD-10-CM code is used to classify granulomatous inflammation of the liver that doesn't fit into other specified categories of liver disease.It excludes acute or subacute hepatitis, chronic hepatitis not otherwise specified, viral hepatitis, and toxic liver disease.

Example 1: A 45-year-old female presents with fatigue, jaundice, and elevated liver enzymes.Liver biopsy reveals granulomatous inflammation.Further investigation fails to identify a specific infectious or toxic cause.K75.3 is assigned., A 60-year-old male with a history of sarcoidosis develops elevated liver enzymes and hepatomegaly.Liver biopsy shows non-caseating granulomas.K75.3 is used to describe the liver involvement secondary to sarcoidosis., A 30-year-old female presents with chronic abdominal pain and elevated liver function tests.Imaging studies show no abnormalities.A liver biopsy is performed, revealing granulomatous changes with no identifiable etiology; the code K75.3 is assigned.

Complete medical history, physical examination findings, laboratory results (liver function tests, inflammatory markers), imaging studies (ultrasound, CT scan, MRI), and liver biopsy report with histopathological findings.Documentation should support the diagnosis of granulomatous hepatitis and exclude other causes.

** Further investigations might include autoimmune serologies, infectious disease testing, and imaging to rule out other conditions before applying this code.The clinical picture should align with the diagnosis of granulomatous hepatitis without a specified etiology.

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