In simple words: Eosinophilic cellulitis is a rare skin condition where the skin becomes inflamed and swollen due to an increase in certain immune cells (eosinophils). It may appear as red, raised, warm, and painful bumps or patches.Doctors usually diagnose it through examination and a tissue sample test. Treatment often involves steroid medications.

Eosinophilic cellulitis [Wells] is a rare inflammatory skin disorder characterized by the infiltration of eosinophils into the subcutaneous tissue. It presents as erythematous, raised, warm, and tender plaques or nodules. The etiology is unknown, but it is believed to be associated with immune-mediated mechanisms.Diagnosis is based on clinical presentation and histopathological examination revealing the presence of eosinophils in the affected tissue. Treatment options typically involve corticosteroids, and in some cases, other immunosuppressive agents.

Example 1: A 45-year-old female presents with tender, erythematous nodules on her arms and legs. Biopsy reveals eosinophilic infiltration, leading to a diagnosis of L98.3.She is treated with oral corticosteroids, showing improvement within a week., A 60-year-old male with a history of inflammatory bowel disease presents with painful plaques on his trunk. Histopathology confirms eosinophilic cellulitis. Treatment consists of topical and systemic corticosteroids, with ongoing monitoring for recurrence., A 28-year-old female with a history of eczema and atopy presents with a flare-up that includes eosinophilic cellulitis of the lower legs.The clinician uses high-potency topical steroids with weekly monitoring.Due to the atopy, a careful consideration of systemic steroid use was performed, which was avoided due to patient history and response to topical therapy.

** Eosinophilic cellulitis is a rare condition.Accurate diagnosis relies on both clinical presentation and histopathological confirmation.The treatment approach may vary depending on disease severity.