2025 ICD-10-CM code M31.7
(Active) Effective Date: N/A Revision Date: N/A Deletion Date: N/A Musculoskeletal and Connective Tissue Diseases - Systemic connective tissue disorders Chapter 13: Diseases of the musculoskeletal system and connective tissue Feed
Microscopic polyangiitis is an inflammation of small and medium-sized blood vessels, potentially damaging organs like kidneys, lungs, and skin.
Medical necessity for treatment of microscopic polyangiitis is established by the presence of characteristic clinical findings and supportive laboratory and imaging evidence of vasculitis affecting multiple organ systems.Treatment is medically necessary to control inflammation, prevent further organ damage, and improve the patient's quality of life.The choice of specific medications and treatment approach will vary depending on the severity of disease and individual patient factors.Documentation must support the diagnosis and the medical necessity for the treatment rendered.
The clinical responsibility for managing microscopic polyangiitis involves a multidisciplinary approach.A rheumatologist often leads the care, coordinating with nephrologists (for kidney involvement), pulmonologists (for lung involvement), neurologists (for neurological manifestations), and dermatologists (for skin involvement).Diagnosis involves detailed history taking, physical examination, laboratory testing (including ANCA), imaging studies, and potentially a biopsy. Treatment focuses on immunosuppression, often using corticosteroids and other immunomodulatory agents, to control inflammation and prevent organ damage. Close monitoring of organ function is crucial throughout the treatment process.
- Chapter 13: Diseases of the musculoskeletal system and connective tissue
- M30-M36 (Systemic connective tissue disorders)
In simple words: Microscopic polyangiitis is a rare disease causing inflammation of small and medium blood vessels. This inflammation can harm organs like your kidneys, lungs, skin, and nerves, leading to symptoms like fatigue, fever, rashes, and shortness of breath. Doctors diagnose it using blood tests, imaging, and tissue samples. Treatment involves anti-inflammatory and immune-suppressing medications.
Microscopic polyangiitis (MPA) is a rare systemic vasculitis characterized by inflammation of small and medium-sized blood vessels.This inflammation can lead to organ damage, affecting various systems including the kidneys (glomerulonephritis), lungs (pulmonary hemorrhage), nervous system (mononeuritis multiplex), skin (purpura), and joints (arthralgia).Diagnosis typically involves clinical presentation, serological testing (antineutrophil cytoplasmic antibodies—ANCA), imaging studies (e.g., CT, MRI), and biopsy of affected tissue. Treatment commonly includes corticosteroids and immunosuppressants to manage inflammation and prevent organ damage. MPA is often considered an autoimmune disorder.
Example 1: A 55-year-old female presents with fatigue, fever, and palpable purpura on her lower extremities.Laboratory tests reveal positive ANCA, and a kidney biopsy confirms glomerulonephritis.A diagnosis of microscopic polyangiitis is made, and treatment with corticosteroids and rituximab is initiated., A 60-year-old male experiences progressive shortness of breath and hemoptysis.Imaging studies show pulmonary hemorrhage, and a lung biopsy reveals vasculitis consistent with MPA.Treatment with corticosteroids and cyclophosphamide is started, with close monitoring of respiratory function., A 40-year-old female develops peripheral neuropathy with weakness and paresthesias in her hands and feet.Nerve conduction studies confirm mononeuritis multiplex.Further investigation reveals positive ANCA and a diagnosis of MPA.Treatment with corticosteroids and azathioprine is implemented, with regular neurological assessments.
* Detailed patient history including onset, progression, and associated symptoms.* Complete physical examination documenting findings relevant to organ system involvement.* Laboratory results, including ANCA testing (specifying the type of ANCA), complete blood count, and renal function tests.* Imaging studies (e.g., chest X-ray, CT scan of the chest, abdomen, or other affected areas; MRI of the nervous system if indicated).* Biopsy report of affected tissue (e.g., kidney, lung, nerve), confirming vasculitis and excluding other conditions.* Documentation of treatment plan, including medications used, dosages, and response to therapy.* Progress notes reflecting clinical course, response to treatment, and any complications.
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- Specialties:Rheumatology, Nephrology, Pulmonology, Neurology, Dermatology
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