2025 ICD-10-CM code M33.21
(Active) Effective Date: N/A Revision Date: N/A Deletion Date: N/A Musculoskeletal and Connective Tissue Diseases - Systemic connective tissue disorders Chapter 13: Diseases of the musculoskeletal system and connective tissue Feed
Polymyositis with respiratory involvement is a systemic inflammatory disease affecting skeletal muscles and causing respiratory complications.
Modifiers are not applicable to ICD-10 codes.
Medical necessity for M33.21 is established by the presence of clinical findings consistent with polymyositis and evidence of respiratory involvement.This may include objective measures of muscle weakness, respiratory compromise, and abnormal laboratory and imaging findings.The severity of symptoms and the need for intervention justify the medical necessity for treatment.
The clinical responsibility includes diagnosis through a comprehensive evaluation incorporating history, physical examination, lab tests, imaging, and potentially biopsy.Treatment involves managing the inflammatory process with corticosteroids and immunosuppressants.Ongoing monitoring for respiratory complications and other systemic manifestations is crucial.
- Chapter 13: Diseases of the musculoskeletal system and connective tissue
- M33.21 falls under the broader category of systemic connective tissue disorders (M30-M36).
In simple words: Polymyositis with respiratory involvement is a condition causing muscle inflammation and weakness, sometimes leading to breathing problems. It affects muscles throughout the body, including those needed for breathing and swallowing. Doctors diagnose it through tests like blood work, muscle biopsies, and imaging. Treatment often involves medications to reduce inflammation and suppress the immune system.
Polymyositis with respiratory involvement is a systemic condition characterized by inflammation and degeneration of skeletal muscles, accompanied by respiratory complications such as pneumonia and respiratory failure.It presents with muscle weakness, tenderness, soft tissue damage, dysphagia (difficulty swallowing), proximal muscle weakness (hips and shoulders), dysarthria (difficulty speaking), and shortness of breath. Diagnosis involves patient history (including cancer history), imaging (MRI), blood tests (muscle enzyme levels, e.g., creatine kinase), muscle biopsy, and urinalysis. Treatment typically includes corticosteroids and immunosuppressants (methotrexate, azathioprine).
Example 1: A 40-year-old female presents with progressive muscle weakness, difficulty swallowing, and shortness of breath.Investigations reveal elevated muscle enzymes, characteristic MRI findings, and a positive muscle biopsy consistent with polymyositis.Respiratory evaluation reveals mild interstitial lung disease. Code M33.21 is used to capture the polymyositis with respiratory involvement., A 65-year-old male with a history of lung cancer develops rapidly progressive muscle weakness and respiratory distress.He is diagnosed with polymyositis with severe respiratory involvement requiring mechanical ventilation.Code M33.21 is utilized, along with codes for the respiratory failure and underlying cancer., A 25-year-old female presents with chronic, slowly progressive muscle weakness, dysphagia, and a persistent cough.Workup reveals elevated muscle enzymes and interstitial lung disease on imaging.A muscle biopsy confirms the diagnosis of polymyositis with respiratory involvement.Code M33.21 is applied, and additional codes might be used to indicate the severity and type of respiratory involvement.
Detailed history of symptoms, physical examination findings focusing on muscle strength and respiratory status, laboratory results (muscle enzymes, inflammatory markers), imaging studies (MRI, chest X-ray, CT scan), biopsy results, and details of any respiratory interventions (e.g., oxygen therapy, mechanical ventilation).
** Always verify the code's validity and appropriateness based on the most current ICD-10-CM guidelines.Consider using additional codes to describe specific respiratory complications (e.g., pneumonia, pleural effusion, respiratory failure).Consult the latest CMS guidelines for coding and reimbursement information.
- Revenue Code: Revenue codes will vary depending on the specific services rendered (e.g., evaluation and management, diagnostic testing, medication administration).Consult your payer's specific coding guidelines.
- RVU: RVUs are not directly associated with ICD-10 codes.Reimbursement is determined by the procedures and services performed, which would use CPT or HCPCS codes with associated RVUs.
- Global Days: Not applicable to ICD-10 codes.
- Payment Status: Active (as of December 3, 2024)
- Modifier TC rule: Not applicable to ICD-10 codes.
- Fee Schedule: Not applicable to ICD-10 codes.
- Specialties:Rheumatology, Pulmonology, Internal Medicine
- Place of Service:Inpatient Hospital, Outpatient Hospital, Office