2025 ICD-10-CM code M35.01
(Revised) Effective Date: N/A Revision Date: N/A Systemic connective tissue disorders - Systemic connective tissue disorders Diseases of the musculoskeletal system and connective tissue (M00-M99) Feed
Sjögren syndrome with keratoconjunctivitis, an autoimmune disease causing dry eyes and mouth due to tear and saliva gland destruction.
Medical necessity for diagnostic and therapeutic interventions for Sjögren's syndrome with keratoconjunctivitis is established by the presence of consistent symptoms (dry eyes and mouth) and confirmation through laboratory findings (ANA, Schirmer's test) and/or biopsy results, indicating the need for appropriate management of the disease to improve patient comfort and prevent potential complications like corneal damage.
Diagnosis involves taking a patient history, conducting physical examinations of the eyes and mouth, performing Schirmer's test, antinuclear antibody (ANA) testing, and potentially a salivary gland biopsy. Treatment may include prescribing eye lubricants, inserting punctal plugs, and using disease-modifying antirheumatic drugs (DMARDs).
- Diseases of the musculoskeletal system and connective tissue (M00-M99)
- Systemic connective tissue disorders (M30-M36)
In simple words: Sjögren's syndrome with keratoconjunctivitis is an autoimmune disease that makes your eyes and mouth dry because it damages the glands that make tears and saliva. It can also cause inflammation in the eyes. Doctors diagnose it using tests and sometimes a tissue sample. Treatment focuses on relieving symptoms like dryness and may include medication.
M35.01, Sjögren syndrome with keratoconjunctivitis, is an autoimmune disease characterized by the destruction of tear and salivary glands, leading to dryness of the eyes (keratoconjunctivitis sicca) and mouth (xerostomia).The condition also involves inflammation of the cornea and conjunctiva.Diagnosis is based on patient history, physical examination of the eyes and mouth, Schirmer's test for tear production, antinuclear antibody (ANA) testing, and potentially a salivary gland biopsy. Treatment focuses on symptomatic relief (e.g., lubricating eye drops, tear duct plugs) and may involve disease-modifying antirheumatic drugs (DMARDs).
Example 1: A 55-year-old female presents with complaints of chronic dry eyes and mouth.She reports difficulty swallowing and a gritty sensation in her eyes.Schirmer's test is abnormal, and ANA testing is positive. A salivary gland biopsy confirms lymphocytic infiltration.Code M35.01 is assigned., A 60-year-old female with a history of rheumatoid arthritis experiences worsening dry eyes and mouth.Her symptoms are consistent with Sjögren's syndrome, and further testing (including ANA and Schirmer's test) confirms the diagnosis. Code M35.01 is assigned., A 40-year-old female reports persistent dry eyes and mouth, along with corneal irritation.A thorough eye examination and laboratory testing (ANA, Schirmer's test) are performed, revealing abnormal findings characteristic of Sjögren syndrome with keratoconjunctivitis.Code M35.01 is applied.
* Complete patient history detailing the onset and duration of symptoms (dry eyes, dry mouth, etc.).* Results of Schirmer’s test quantifying tear production.* Results of antinuclear antibody (ANA) testing.* Salivary gland biopsy report (if performed) demonstrating lymphocytic infiltration.* Comprehensive ophthalmologic examination findings.* Documentation of any prescribed treatments (e.g., lubricating eye drops, punctal plugs, DMARDs).
** This code is specific to Sjögren's syndrome with the ophthalmologic manifestation of keratoconjunctivitis.If other manifestations are present, additional codes may be necessary.
- Payment Status: Active
- Specialties:Rheumatology, Ophthalmology
- Place of Service:Office, Hospital, Outpatient Clinic