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2025 ICD-10-CM code N46.02

Azoospermia due to extratesticular causes.

Use additional codes to identify the specific extratesticular cause of azoospermia, if known (e.g., N46.021, Azoospermia due to drug therapy; N46.024, Azoospermia due to radiation).

Medical necessity for the evaluation and treatment of azoospermia is established by the patient's desire for fertility and the presence of azoospermia confirmed by semen analysis.Further testing to determine the underlying cause of azoospermia is also medically necessary to guide appropriate treatment strategies.

Diagnosis and treatment of male infertility are typically managed by urologists, reproductive endocrinologists, or primary care physicians.Evaluation may include a physical examination, semen analysis, hormone testing, genetic testing, and imaging studies. Treatment depends on the underlying cause of azoospermia.

In simple words: This code indicates a male's inability to fertilize an egg due to the absence of sperm, specifically caused by factors outside the testicles.

Azoospermia due to extratesticular causes.Azoospermia is the absence of sperm in the semen. Excludes1: vasectomy status (Z98.52)

Example 1: A 35-year-old male presents with an inability to conceive after one year of unprotected intercourse. Semen analysis reveals azoospermia. Further investigation reveals exposure to radiation therapy for a previous cancer diagnosis. The diagnosis N46.02 is assigned., A 28-year-old male with a history of cystic fibrosis presents for evaluation of infertility. Semen analysis confirms azoospermia due to congenital bilateral absence of the vas deferens (CBAVD). The diagnosis N46.02 is assigned., A 40-year-old male undergoing chemotherapy for lymphoma presents with concerns about fertility. Semen analysis reveals azoospermia secondary to the chemotherapy treatment. The diagnosis N46.02 is assigned, specifically N46.021 (Azoospermia due to drug therapy).

Documentation should include medical history, physical exam findings, semen analysis results, and any relevant diagnostic testing, such as hormone levels, genetic testing, imaging studies (e.g., ultrasound, MRI), or biopsy results.

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