Start New EnglishEspañol中文РусскийالعربيةTiếng ViệtFrançaisDeutsch한국어Tagalog Library Performance

2025 ICD-10-CM code O88.1

Amniotic fluid embolism; a rare and life-threatening obstetric complication.

Code O88.1 should only be used for maternal records.Do not use this code for newborn records.Additional codes from Z3A (Weeks of gestation) may be used to specify the week of gestation if known.

Medical necessity is established by the presence of clinical indicators consistent with AFE, including sudden onset of respiratory distress, hypotension, coagulopathy, and altered mental status during or immediately following labor, delivery, or termination of pregnancy. Documentation of appropriate diagnostic and therapeutic interventions must support medical necessity.

Obstetrician/Gynecologist, Anesthesiologist, Intensivist

IMPORTANT Anaphylactoid syndrome of pregnancy

In simple words: Amniotic fluid embolism is a rare and dangerous condition that can happen during pregnancy, childbirth, or shortly after.It occurs when amniotic fluid containing fetal cells enters the mother's bloodstream, causing a severe reaction that can lead to breathing problems, low blood pressure, and other life-threatening complications.

Amniotic fluid embolism (AFE) is a rare but serious obstetric emergency characterized by the entry of amniotic fluid and fetal elements into the maternal circulation. This can lead to sudden cardiovascular collapse, disseminated intravascular coagulation (DIC), and potentially death.Symptoms typically manifest during labor, cesarean delivery, or within 30 minutes postpartum and may include acute dyspnea and cough, acute hypotension, encephalopathy with altered mental status and seizures, hypoxia and cyanosis, coagulopathy, severe hemorrhage, uterine atony, acute pulmonary hypertension, and cardiac arrest.The condition is classified as anaphylactoid syndrome of pregnancy.

Example 1: A 35-year-old woman presents during labor with sudden shortness of breath, hypotension, and altered mental status.Diagnosis of AFE is suspected, and emergency treatment is initiated, including supportive care and management of DIC. , A 28-year-old woman undergoes a cesarean section. Post-procedure, she experiences acute respiratory distress, hypoxia, and hemorrhaging.AFE is suspected, and the patient is transferred to the ICU for immediate management., A 40-year-old woman delivers vaginally.Within 15 minutes of delivery, she shows signs of DIC, severe hypotension, and respiratory compromise.Rapid diagnosis and emergency resuscitation are crucial for survival.

Complete maternal medical history, including details of the pregnancy and delivery.Comprehensive documentation of vital signs, respiratory status, coagulation studies, laboratory results, and treatment administered.Detailed description of any symptoms, including timing and severity.Detailed notes on any medications or interventions administered and response to those interventions.

** AFE is a rare but potentially fatal condition requiring rapid diagnosis and aggressive management. Mortality rates remain high despite advancements in treatment.Early recognition and prompt intervention are critical to improving outcomes.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

Discover what matters.

iFrame™ AI's knowledge is aligned with and limited to the materials uploaded by users and should not be interpreted as medical, legal, or any other form of advice by iFrame™.