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2025 ICD-10-CM code O91.21

Nonpurulent mastitis associated with pregnancy. This includes gestational interstitial mastitis, gestational lymphangitis of breast, gestational mastitis NOS, and gestational parenchymatous mastitis.

Use additional code to identify infection, if present. Do not use this code on the newborn record. This code requires a 7th character extension to indicate the trimester of pregnancy.

Medical necessity for treatment of nonpurulent mastitis is established by the presence of signs and symptoms such as pain, swelling, redness, and tenderness in the breast during pregnancy. The documentation should support the diagnosis and the need for intervention to alleviate symptoms and prevent complications.

IMPORTANT:For mastitis associated with the puerperium (the period after childbirth) or lactation, use O91.22 and O91.23, respectively. Use additional codes to identify any associated infection.

In simple words: This code describes inflammation of the breast during pregnancy that does not involve a pus-producing infection.

Nonpurulent mastitis associated with pregnancy encompasses various forms of breast inflammation without pus formation during pregnancy. These include gestational interstitial mastitis (inflammation of the connective tissue of the breast), gestational lymphangitis of the breast (inflammation of the lymphatic vessels in the breast), and gestational parenchymatous mastitis (inflammation of the functional breast tissue). It also includes gestational mastitis NOS (not otherwise specified) for cases where a more specific diagnosis is not available.

Example 1: A pregnant woman in her second trimester presents with breast pain, swelling, and redness, but no fever or signs of infection. After examination, she is diagnosed with nonpurulent mastitis associated with pregnancy., A pregnant woman in her first trimester experiences tenderness and inflammation in her breast. A breast ultrasound rules out abscess formation, and the diagnosis is nonpurulent interstitial mastitis associated with pregnancy., A woman in her third trimester presents with redness and streaking on her breast, consistent with lymphangitis. She has no fever or other systemic symptoms, and the diagnosis is nonpurulent gestational lymphangitis of the breast.

Documentation should clearly indicate the type of mastitis (e.g., interstitial, lymphangitis, parenchymatous), the absence of purulent discharge, and the association with pregnancy. Any diagnostic tests performed (e.g., ultrasound) should also be documented. If an infection is present, it should be coded separately.

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