2025 ICD-10-CM code P55
Hemolytic disease of newborn. This condition arises due to blood group incompatibility between mother and newborn.
Medical necessity for the treatment of HDN is established by the presence of signs and symptoms of the disease, such as hyperbilirubinemia and anemia. Treatment is medically necessary to prevent serious complications, including kernicterus (brain damage due to high bilirubin levels), heart failure, and even death.
Diagnosis and management of hemolytic disease of the newborn (HDN) is primarily the responsibility of pediatricians and neonatologists.Obstetricians are also involved in the prenatal monitoring and management of pregnancies at risk for HDN.Other specialists may be consulted based on the severity of the condition and any associated complications.
- 16 Certain conditions originating in the perinatal period
- P50-P61 Hemorrhagic and hematological disorders of newborn
In simple words: A baby's red blood cells are attacked by antibodies from the mother's blood because of different blood types.
Hemolytic disease of the newborn (HDN), also known as erythroblastosis fetalis, is a condition where the red blood cells of a fetus or newborn are destroyed by antibodies produced by the mother. This typically happens when the mother and baby have incompatible blood types, most commonly involving the Rh factor or ABO blood groups.
Example 1: A newborn presents with jaundice and anemia within the first 24 hours of life. Blood tests reveal Rh incompatibility with the mother, confirming a diagnosis of Rh hemolytic disease., A newborn with type A blood is born to a mother with type O blood. The infant develops mild jaundice and anemia a few days after birth, consistent with ABO hemolytic disease., A pregnant woman with Rh-negative blood undergoes routine prenatal antibody screening, which shows rising antibody titers against Rh-positive blood.This indicates a potential for Rh hemolytic disease in the fetus, necessitating close monitoring and possible interventions.
Documentation should include evidence of blood group incompatibility between mother and newborn, such as blood typing results, antibody screening results, and Coombs test results. The newborn's clinical presentation, including signs of jaundice, anemia, and other related complications, should also be documented.
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