2025 ICD-10-CM code Q95
Balanced rearrangements and structural markers, not elsewhere classified. Includes: Robertsonian and balanced reciprocal translocations and insertions.
The medical necessity for genetic testing and subsequent use of Q95 is established when individuals present with specific indications, such as developmental delays, intellectual disability, multiple congenital anomalies, infertility, or recurrent miscarriages, suggesting a potential underlying chromosomal abnormality.Genetic counseling is essential to help individuals understand the implications of carrying a balanced rearrangement.
Clinical responsibility for diagnosing and managing Q95 typically falls under the purview of geneticists, genetic counselors, and other specialists involved in diagnosing and treating genetic disorders. They interpret karyotypes and other genetic tests to identify these chromosomal rearrangements.If a patient presents with developmental delays, infertility, or recurrent miscarriages, healthcare providers may order genetic testing to investigate potential underlying chromosomal abnormalities, including balanced rearrangements.
In simple words: This code represents a balanced rearrangement of chromosomes or structural markers that are not classified elsewhere. This includes Robertsonian translocations, balanced reciprocal translocations, and insertions where genetic material is rearranged but no genetic material is lost or gained.
Balanced rearrangements and structural markers, not elsewhere classified. Includes: Robertsonian and balanced reciprocal translocations and insertions.
Example 1: A 35-year-old woman experiencing recurrent miscarriages undergoes genetic testing. Karyotyping reveals a balanced Robertsonian translocation, which is coded as Q95., A couple seeking fertility treatment undergoes genetic screening. The male partner is found to have a balanced reciprocal translocation, coded as Q95., A child with developmental delays undergoes chromosomal analysis. The results show a balanced insertion, again classified under Q95.
Documentation for Q95 should include a detailed report of the chromosomal analysis, specifically karyotyping or other genetic testing methods employed, identifying the specific type of balanced rearrangement (e.g., Robertsonian translocation, reciprocal translocation, insertion), and the chromosomes involved. Any phenotypic manifestations or associated clinical conditions should also be documented.
** Individuals with balanced rearrangements often do not exhibit any phenotypic abnormalities themselves; however, they have an increased risk of having children with unbalanced chromosomal rearrangements, which can lead to various congenital anomalies, developmental delays, or intellectual disability.
- Specialties:Genetics, Genetic Counseling, Obstetrics and Gynecology (for recurrent miscarriages), Pediatrics (for developmental delays), Reproductive Endocrinology (for infertility)
- Place of Service:Office, Outpatient Hospital, Independent Clinic, Genetic Testing Laboratory