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2025 ICD-10-CM code R53.82

Chronic fatigue, unspecified; this code is used when a patient presents with chronic fatigue that cannot be attributed to a more specific diagnosis.

Consult the official ICD-10-CM coding guidelines for the most up-to-date information.This code is for unspecified chronic fatigue only when other causes have been appropriately ruled out.

Medical necessity is established when the patient experiences significant and persistent fatigue that affects daily life, despite a thorough workup failing to identify an underlying cause.The level of impact on daily activities and the exclusion of other diagnoses support the medical necessity for further investigation and management.

The clinical responsibility involves a thorough history taking, physical examination, and investigations to exclude other causes of fatigue, such as anemia, hypothyroidism, infections, or underlying medical conditions.This requires a comprehensive assessment to rule out other diagnoses.

IMPORTANT:R53.83 (Other fatigue) may be considered if the specific criteria for R53.82 are not fully met.Before October 1, 2022, this code was often used as a placeholder for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).Since then, G93.32 is the designated code for ME/CFS.Careful consideration should be given to differentiate R53.82 from other causes of fatigue.

In simple words: This code means the doctor recorded that you have long-lasting tiredness that they can't explain yet after doing tests or looking for other reasons.

This ICD-10-CM code, R53.82, signifies chronic fatigue that remains uncategorized after thorough investigation.It's applied when the patient experiences persistent and excessive tiredness not explained by other identifiable medical conditions or specific diagnoses, such as chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME).The diagnosis necessitates a comprehensive evaluation to rule out other potential causes.

Example 1: A patient presents with persistent fatigue lasting over six months, with no improvement despite adequate rest and no identifiable underlying medical condition., A patient reports chronic fatigue that interferes with daily activities, but investigations reveal no specific cause, such as infection, hormonal imbalances, or nutritional deficiencies., Following initial assessment for fatigue, a patient fails to return for additional testing, preventing the establishment of a definitive diagnosis; this code is used until additional information is obtained.

Detailed medical history documenting the onset, duration, and severity of fatigue; comprehensive physical examination findings; results of relevant laboratory tests (e.g., complete blood count, thyroid function tests); documentation of efforts to rule out other potential diagnoses.

** This code should only be used as a last resort when other causes of fatigue have been completely excluded.Ongoing research and development might lead to a better understanding of unspecified chronic fatigue.

** Only Enterprise users with EHR integration can access case-specific answers. Click here to request access.

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