2025 ICD-10-CM code R77.1
(Active) Effective Date: N/A Revision Date: N/A Deletion Date: N/A Symptoms, signs, and abnormal clinical and laboratory findings - Other abnormalities of plasma proteins Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99) Feed
This code signifies an abnormality specifically in globulin levels within the blood, without a more precise diagnosis available.
Medical necessity is established by the presence of an abnormal globulin level detected on laboratory testing, raising concerns about potential underlying pathology that requires further evaluation.Further investigation is justified to rule out serious conditions.
The clinical responsibility for this code lies with the physician or healthcare professional who orders and interprets the blood tests revealing the globulin abnormality.They are responsible for determining whether further investigations are required to establish the underlying cause.
- Chapter 18: Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R99)
- R77 (Other abnormalities of plasma proteins)
In simple words: This code means there's a problem with a certain type of protein in your blood (called globulin), but doctors don't yet know exactly what's causing it.
R77.1, Abnormality of globulin, denotes an identified irregularity in the globulin fraction of blood plasma proteins.This code is applied when a specific underlying cause for the altered globulin levels cannot be determined, despite investigation.It is used in situations where other, more definitive diagnoses are not possible, leaving only the generalized abnormality of globulin to be recorded. The code is under the broader category of abnormal findings on examination of blood, not further specified.
Example 1: A patient presents with fatigue and recurrent infections. Blood tests reveal an elevated globulin level.Further investigation, including immunologic workup and bone marrow biopsy, is inconclusive. R77.1 is assigned as the most accurate diagnosis reflecting the abnormal findings., During a routine health check, an elevated gamma globulin level is detected in a patient's blood work. The physician determines additional testing is warranted but does not find an underlying cause after further investigation.The patient is advised of the abnormality and scheduled for follow-up testing. The code R77.1 is used to capture the detected abnormality., A patient is referred to a hematologist due to an unexplained, persistent elevation of globulin detected in blood testing.Extensive hematological work-up fails to identify a definitive diagnosis.R77.1 is utilized pending further investigation or resolution of the anomaly.
Complete blood count (CBC) with differential, serum protein electrophoresis (SPE), and potentially further specialized testing depending on the clinical context (e.g., immunofixation electrophoresis, immunoglobulins levels, bone marrow biopsy).
** This code should only be used when a more specific diagnosis related to the globulin abnormality is not established after appropriate investigation.The code does not imply a specific disease process, only an abnormal laboratory finding.
- Payment Status: Active
- Specialties:Hematology, Immunology, Internal Medicine
- Place of Service:Office, Hospital Inpatient, Hospital Outpatient, Laboratory