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2025 ICD-10-CM code R77.8

This ICD-10-CM code classifies other specified abnormalities detected in plasma proteins during a blood examination, where no more precise diagnosis is available.

Consult the official ICD-10-CM coding guidelines for the most up-to-date rules and regulations.

Medical necessity is established by the presence of abnormal plasma protein findings on blood test.Further investigation is medically necessary to determine the underlying cause and direct appropriate management.

The clinical responsibility for this code lies with the physician or healthcare professional who orders and interprets the blood test results. They are responsible for documenting the findings and performing any necessary follow-up investigations to determine the underlying cause of the plasma protein abnormalities.

IMPORTANT:Refer to the Alphabetical Index of the ICD-10-CM for guidance on selecting the most appropriate code if more specific information becomes available.Consider codes within the R70-R79 range for other blood abnormalities. If specific plasma protein abnormalities are identified (e.g., hypoalbuminemia, hypergammaglobulinemia), use the appropriate code from other chapters.

In simple words: This code is used when a blood test shows an unusual level of plasma proteins, but doctors don't know the exact cause yet.

R77.8 in the ICD-10-CM classification system denotes other specified abnormalities of plasma proteins identified during blood examination.This code is applied when a blood test reveals irregularities in plasma proteins, but further investigation is needed to establish a definitive diagnosis.The code is used when the abnormalities are not otherwise specified or fall outside of more specific categories within the R70-R79 block (Abnormal findings on examination of blood, without diagnosis).

Example 1: A patient presents with generalized edema.A blood test reveals hypoalbuminemia, but the cause (e.g., nephrotic syndrome, liver disease) is not yet determined. R77.8 is used pending further investigation., A routine blood panel shows an unexplained elevation of certain plasma proteins.No clinical symptoms are present. R77.8 is used as a placeholder until the reason for the elevation is established., A patient with chronic kidney disease undergoes regular blood monitoring.The results show abnormal plasma protein levels, but the specific nature of the abnormality needs further clarification.R77.8 is used pending additional testing.

Complete blood count (CBC) report, serum protein electrophoresis results, detailed clinical history, physical examination findings, any additional diagnostic testing (e.g., liver function tests, renal function tests) performed to investigate the cause of the plasma protein abnormalities.

** This code is intended for use when insufficient information is available to assign a more specific code.Always review the Alphabetical Index to ensure appropriate code selection.

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