2025 ICD-10-CM code R87.610
Atypical squamous cells of undetermined significance (ASC-US) detected on a Pap smear of the cervix.
Medically necessary for screening and early detection of cervical cancer. Follow-up procedures, such as colposcopy or biopsy, are medically necessary if HPV testing is positive or if repeat Pap smears continue to show ASC-US.
Ordering and interpreting the Pap smear results, and determining the appropriate follow-up based on the ASC-US finding. This may include repeat Pap smears, HPV testing, or colposcopy.
- 18
- Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis (R83-R89)
In simple words: The Pap smear results showed some slightly unusual cells, but it's not clear if they are precancerous or due to other causes like an infection.
Atypical squamous cells of undetermined significance on cytologic smear of cervix (ASC-US). This indicates that some cells on the Pap smear appear slightly abnormal, but it's unclear whether these changes are caused by a precancerous condition or something else, such as an infection or inflammation.
Example 1: A 25-year-old woman has a routine Pap smear that shows ASC-US. The physician orders an HPV test, which is negative. The patient is advised to have a repeat Pap smear in one year., A 30-year-old woman's Pap smear shows ASC-US. An HPV test is positive for high-risk HPV. The physician recommends a colposcopy to examine the cervix more closely., A 45-year-old woman with a history of abnormal Pap smears has another Pap smear showing ASC-US. The physician recommends a colposcopy and biopsy to evaluate the cervical cells further.
Details of the Pap smear results, including the presence of ASC-US and any associated findings. Results of HPV testing, if performed. Recommendations for follow-up care, such as repeat Pap smear, colposcopy, or biopsy.