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BETA v.3.0

2025 ICD-10-CM code T39.1X5A

Adverse effect of 4-Aminophenol derivatives, initial encounter.

Use a secondary code from Chapter 20 (External causes of morbidity) to indicate the cause of the adverse effect, if known. Use additional codes to specify manifestations of poisoning (e.g., liver damage). Do not use this code for underdosing of a medication.

The medical necessity of this code is established by the presence of an adverse effect due to the use of a 4-aminophenol derivative, requiring medical intervention.

The provider is responsible for documenting the specific 4-aminophenol derivative causing the adverse effect, the nature of the adverse effect, and the treatment provided.

In simple words: This code indicates a bad reaction to a drug like acetaminophen (Tylenol) when you first seek medical care for it.

This code describes an adverse reaction to a 4-aminophenol derivative, such as acetaminophen.It is used for the initial encounter.

Example 1: A patient presents to the emergency room with nausea and vomiting after taking an overdose of acetaminophen., A patient develops a rash after taking a prescribed medication containing a 4-aminophenol derivative., A patient experiences liver damage after chronic use of acetaminophen.

Documentation should include the drug causing the adverse reaction, the specific symptoms experienced, and any diagnostic tests performed. If the reaction is due to a combination product, identify the specific ingredient when possible.

** For underdosing, use codes Z91.12- or Z91.13-. If the adverse effect is due to an interaction with another substance, such as alcohol, a code from category T51 should also be assigned.

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