2025 ICD-10-CM code T46.2X5S

Sequela of adverse effect of other antidysrhythmic drugs.

The seventh character in this code (S) indicates a sequela.Always code the underlying condition (the initial adverse reaction) separately if known.

Modifiers might be applicable depending on the specific circumstances of the encounter and the services provided (e.g., modifiers for the place of service or the type of visit).

Medical necessity is established by evidence of a causal relationship between the prior adverse reaction to the antidysrhythmic drug and the current sequelae. The documentation should clearly demonstrate the temporal relationship, clinical findings, and the impact of the sequelae on the patient's health status.The treatment should be medically appropriate for managing the identified long-term effects.

The clinical responsibility involves documenting the initial adverse reaction to the antidysrhythmic drug, the subsequent evaluation of the sequelae, and the management of any resulting complications.This may include electrocardiograms (ECGs), echocardiograms, cardiac enzyme tests, and other investigations to determine the extent of damage.

IMPORTANT Related codes include T46.2X5A (initial encounter) and T46.2X5D (subsequent encounter) for the adverse effect itself, not the sequela.Additional codes may be necessary depending on the specific sequelae experienced by the patient (e.g., codes from chapters relating to cardiac, neurological, or other affected organ systems).

In simple words: This code is for long-term problems that happen after a reaction to a heart rhythm medication (other than those specifically listed elsewhere).It's used when the original reaction happened before, and now there are ongoing health issues as a result.

This code classifies the late effects (sequelae) resulting from an adverse reaction to antidysrhythmic drugs not otherwise specified.It indicates that the adverse effects occurred in the past and are now manifesting as long-term consequences.The initial adverse event should be coded separately if known.Additional codes may be necessary to specify the nature of the sequela and any associated conditions.

Example 1: A patient experiences a prolonged QT interval following initiation of amiodarone therapy several months prior. The prolonged QT interval is documented as a sequela of the adverse effect.T46.2X5S would be used to describe the long-term consequence of the earlier amiodarone-induced arrhythmia., A patient develops heart failure months after starting a new antiarrhythmic medication.The heart failure is considered a direct consequence of the drug's adverse effect,making T46.2X5S appropriate in addition to a code specifying the heart failure.Appropriate documentation would include the prior cardiac evaluation., A patient presents with unexplained syncope and is found to have developed cardiomyopathy following a prior adverse reaction to flecainide. This cardiomyopathy represents a sequela of the previous adverse effect.T46.2X5S is utilized to reflect this long-term consequence,alongside codes describing cardiomyopathy and syncope.

Documentation should include:* Detailed history of the initial adverse drug reaction, including the specific antidysrhythmic drug involved, the timing of the reaction, and the symptoms experienced.* Comprehensive clinical examination findings, including cardiac assessments (ECG, echocardiogram).* Laboratory results (cardiac enzymes, electrolytes).* Imaging studies (if indicated).* Documentation of the sequelae, including their onset, severity, and impact on the patient's functional status.* Treatment plan for managing the sequelae.

** This code should only be used when the sequela is a direct result of a previously documented adverse reaction to an antidysrhythmic drug.If the relationship is uncertain, additional investigation and clarification may be needed.

  • Payment Status: Active
  • Specialties:Cardiology, Internal Medicine, Clinical Pharmacology
  • Place of Service:Office, Hospital Inpatient, Hospital Outpatient, Skilled Nursing Facility
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