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2025 ICD-10-CM code T80.4

Rh incompatibility reaction due to blood or blood product transfusion.

Follow official ICD-10-CM coding guidelines and conventions for accurate coding. Additional codes should be used to fully describe the type and severity of the reaction and any associated complications.

Modifiers may be applicable depending on the circumstances of the transfusion and any additional procedures performed. Consult current coding guidelines for appropriate modifier usage.

Medical necessity is established based on the need for blood transfusion due to significant blood loss, anemia, or other conditions requiring blood volume replacement. The documentation must support the clinical need for the blood transfusion.

The clinical responsibility lies with the healthcare provider overseeing the blood transfusion and managing any resulting complications. This typically involves a hematologist, transfusion medicine specialist, or the attending physician responsible for the patient's overall care.

IMPORTANT:Additional codes may be necessary to specify the type of reaction (e.g., hemolytic reaction) or any associated complications.Codes from Chapter 20 (External causes of morbidity) should be used to indicate the cause of the transfusion reaction, if applicable.Additional codes may be used to identify any retained foreign body (Z18.-).

In simple words: This code is used when someone has a bad reaction after a blood transfusion because their blood type and the donated blood don't match up well.The reaction happens because of differences in Rh factors in the blood.

This code classifies an Rh incompatibility reaction resulting from a transfusion of blood or blood products.It encompasses adverse reactions stemming from the incompatibility of Rh antigens between the transfused blood and the recipient's blood. This reaction can manifest in various ways, and further diagnostic codes might be necessary to specify the precise clinical presentation.

Example 1: A 65-year-old male patient with severe anemia receives a blood transfusion. Following the transfusion, he experiences fever, chills, and back pain, indicative of an acute hemolytic transfusion reaction.This is coded as T80.4, along with codes specifying the hemolytic reaction and any additional complications., A 30-year-old female patient undergoing surgery requires multiple units of packed red blood cells. Post-operatively, she develops mild jaundice and elevated bilirubin levels, suggestive of a delayed hemolytic transfusion reaction. This is coded as T80.4, supplemented by codes describing the delayed onset and severity of the reaction., A 25-year-old pregnant woman with Rh incompatibility requires prophylactic anti-D immunoglobulin to prevent Rh alloimmunization. However, she experiences an allergic reaction following administration.This would be coded as T80.4, with additional codes specifying the allergy and the type of blood product administered.

Comprehensive documentation should include the patient's blood type, Rh factor, pre-transfusion and post-transfusion lab values (complete blood count, antibody screen, direct antiglobulin test), detailed description of the reaction, including timing and severity of symptoms, treatment administered, and response to treatment.Any complications should also be thoroughly documented.

** This code should be used cautiously.Precise clinical documentation is crucial for appropriate coding.Always refer to the latest ICD-10-CM guidelines and official coding resources for the most up-to-date information.

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