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2025 ICD-10-CM code T80.5

Anaphylactic reaction due to serum.

Always use appropriate additional codes to specify the type of serum, and to identify any other complications or co-morbidities.Refer to the latest ICD-10-CM guidelines for complete coding instructions.Ensure the use of appropriate external cause codes from Chapter 20 if required.

Medical necessity for coding T80.5 is established by the presence of an anaphylactic reaction directly attributable to serum administration. Documentation must support a clear causal relationship between the serum and the reaction. This typically involves a temporal relationship between serum administration and the onset of symptoms, and a clinical picture consistent with anaphylaxis.

The clinical responsibility for coding this diagnosis rests with the physician who manages the patient's anaphylactic reaction.This includes recognizing the symptoms, implementing appropriate treatment (such as epinephrine administration), and documenting the event thoroughly in the patient's medical record.

IMPORTANT:Additional codes may be necessary to specify the type of serum involved, and codes from Chapter 20 (External causes of morbidity) should be used to identify the cause of the anaphylactic reaction.Excludes codes for other allergic reactions or shock.

In simple words: This code is for a serious allergic reaction (anaphylaxis) caused by serum (the clear part of blood). This reaction can be very dangerous and happen quickly after coming into contact with the serum. It causes symptoms like rash, swelling, breathing trouble, and low blood pressure.

This code classifies anaphylactic reactions specifically caused by serum.Anaphylaxis is a severe, life-threatening allergic reaction that can occur within minutes of exposure to an allergen.In this context, the allergen is serum, which is the liquid component of blood that remains after clotting factors have been removed. Symptoms can include hives, swelling, difficulty breathing, and a drop in blood pressure. This code is used to report the complication itself, and additional codes may be required to specify the type of serum and the external cause.It excludes allergic reactions or shock not specifically caused by serum.

Example 1: A patient receiving an antivenom serum develops hives, shortness of breath, and hypotension shortly after the injection.T80.5 is coded to reflect the anaphylactic reaction, with additional codes potentially used for the specific type of antivenom and the underlying condition requiring the antivenom., A patient undergoing treatment with a tetanus serum develops symptoms of anaphylaxis, such as widespread urticaria, angioedema, and respiratory distress. T80.5 is used to document the anaphylactic reaction, alongside additional codes to document the type of serum used, and any additional medical interventions., During a routine serum injection, a patient experiences rapid onset of hypotension, tachycardia, and bronchospasm.T80.5 is the primary code, with additional codes to identify the type of serum, any concurrent diagnoses, and any other treatments administered, such as epinephrine and airway support.

Detailed documentation is essential and should include the following:*The type of serum administered.*The timing of the administration relative to the onset of symptoms.*A complete description of the patient's symptoms.*The treatments administered.*The patient's response to treatment.*The specific type of serum.*Any other relevant details, such as the patient's medical history.

** This code is for anaphylactic shock specifically due to serum.It is critical to carefully document the type of serum and other relevant details to ensure accurate coding.

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