2025 ICD-10-CM code T80.6
(Active) Effective Date: N/A Revision Date: N/A Deletion Date: N/A Injury, poisoning and other consequences of external causes - Other serum reactions Injury, poisoning and certain other consequences of external causes Feed
Other serum reactions, including intoxication by serum, protein sickness, serum rash, serum sickness, and serum urticaria.
Medical necessity is established by the presence of clinical symptoms consistent with a serum reaction, and the temporal relationship to the administration of serum.Supporting documentation, such as laboratory results, is crucial for demonstrating medical necessity.
The clinical responsibility will depend on the specific symptoms and severity of the reaction. It may involve allergists, immunologists, or other specialists depending on the complexity of the case.
- Injury, poisoning and certain other consequences of external causes
- T80-T88 (Complications of surgical and medical care, not elsewhere classified)
In simple words: This code is for different health problems that happen after someone is exposed to serum (a part of blood).These problems can include a rash, sickness, or swelling.
This code encompasses a variety of adverse reactions following exposure to serum, excluding serum hepatitis (B16-B19).Specific reactions included are intoxication by serum, protein sickness, serum rash, serum sickness, and serum urticaria.The code excludes complications such as bone marrow transplant rejection (T86.01), febrile nonhemolytic transfusion reaction (R50.84), fluid overload due to transfusion (E87.71), posttransfusion purpura (D69.51), transfusion-associated circulatory overload (TACO) (E87.71), transfusion (red blood cell)-associated hemochromatosis (E83.111), transfusion-related acute lung injury (TRALI) (J95.84).
Example 1: A patient develops a widespread rash and hives (urticaria) following an intravenous immunoglobulin (IVIG) infusion.T80.6 is used to code the serum sickness reaction., A patient experiences fever, joint pain (arthropathy), and a skin rash after receiving a tetanus booster shot, consistent with a serum sickness-like reaction. T80.6 is used, along with a code from Chapter 20 to indicate the immunization as the external cause., A patient presents with symptoms of serum sickness after receiving antivenom for a snake bite.The serum sickness is coded as T80.6, with an additional code from Chapter 20 specifying the snake bite (external cause).
Detailed history of serum exposure, including type of serum, route of administration, and date of administration. Thorough physical examination documenting the rash, urticaria, fever, and other symptoms.Laboratory tests (if any) to support the diagnosis, including serum levels and allergy testing.
** This code is for adverse reactions specifically related to serum, and not other forms of allergic reactions or hypersensitivity.Differential diagnosis is essential to differentiate this from other conditions.
- Payment Status: Active
- Specialties:Allergy and Immunology, Internal Medicine
- Place of Service:Office, Hospital Inpatient, Hospital Outpatient